Effect on the body
The drug affects certain areas of the central nervous system. The main active ingredient of the drug interacts with a hormone called serotonin. This relationship helps to influence the areas of the brain that are responsible for the feeling of hunger. As a result, appetite decreases.
At the same time, there is an impact on the areas of the central nervous system responsible for the feeling of satiety with food. This allows you to get maximum satiety with minimal food consumption. As a result, those losing weight reduce the portion size several times. This allows a person to quickly lose weight.
While taking the drug, the stomach decreases several times. This means that a person will not switch to the previous nutrition system after completing the course of using the product.
Short description
Trade names: Lorcaserin, Belviq, formerly Lorqess.
ATC code: A08AA11 (drugs that affect the gastrointestinal tract and metabolism, for the treatment of obesity with central action).
Main active ingredient: (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine.
Chemical formula: C11H14ClN.
Structural formula:
Molecule:
Release form: capsules and tablets.
Packing:
- 60 round blue tablets of 10 mg each with imprints (10 on one side, A on the other) in a plastic jar with a screw cap;
- 60 bright orange capsules of 10 ml each in a plastic jar with a screw cap;
- white powder (Lorcaserin HCL powder) without a characteristic taste or odor, quickly dissolving in water, sold in vacuum packaging, 500 g.
Manufacturers:
- Arena Pharma (USA);
- Supreme Sweet Life (USA);
- AASraw Biochemical Technology Co (USA).
Main purpose: weight loss by reducing appetite.
Method of administration: oral.
Excretion from the body: within 11 hours, mainly by the kidneys, in small quantities - with feces.
Efficacy of the drug
The effectiveness of the product has been confirmed by clinical studies. According to tests, the drug does not cause as much harm to health as other drugs. In this regard, the manufacturer received permission to sell the product.
More than 8,000 people took part in the study. The people were divided into two groups. However, some took the drug, others took simple vitamins under the guise of weight loss. Along with consuming the product, those losing weight were prescribed to follow a diet and increase physical activity. As a result, the group taking the drug had 5% better scores.
At the end of the test the following results were recorded. 90% of people in the group taking the drug lost excess weight. Those losing weight lost from 5.8 to 40% of their initial body weight in 12 months. It was also recorded that the group taking the drug had stabilized blood pressure and normalized the concentration of cholesterol in the blood.
The essence of the novelty
So, what is this drug? It is also known as Belvik. This is an innovative drug that relieves excess weight. It was registered in the USA by the creator of a pharmaceutical company. The potential audience was vast, because both men and women suffer from excess fat mass. In particularly advanced cases, obesity causes complications on the heart and other organs, accompanied by shortness of breath, increased sweating, fatigue and decreased libido. Every year, obesity becomes “younger” and manifests itself in very young people, depriving them of hope for a normal life. Many overweight people appear extremely healthy and active. In public, they utter dubious maxims regarding attractiveness at any weight and the seductive softness of curvy figures, but most often behind the apparent self-confidence lie complexes and an inability to take control of their nutrition. An auxiliary remedy in such a situation will be a special complex for weight loss.
Contraindications
The drug has the following contraindications:
- Atypical reactions of the body to taking the drug in the form of itching of the epidermis, rashes or swelling of soft tissues,
- Age up to 18 years,
- Individual intolerance to the product,
- The period of pregnancy or lactation.
Even in the absence of contraindications, it is not recommended to use the product without consulting a doctor.
Side effects
Taking the drug may cause the following side effects:
- Problems with bowel movements,
- dizziness,
- Dry mouth
- Cardiopalmus,
- Temperature increase
- Pain in joints and muscles,
- Deterioration of vision and hearing,
- Problems with urination,
- Chills,
- Cough,
- Sneezing,
- Hypersweating,
- Runny nose,
- Nausea accompanied by vomiting
- A sore throat.
In some cases, breathing and heart problems occur, and depression appears.
Overdose
If the dose of the drug is increased, the following consequences may occur:
- Headache,
- Nausea accompanied by vomiting
- Memory problems
- Depressed state
- Lack of bowel movements for several days
- Rapid pulse,
- Dry mouth,
- Drug dependence.
How to use
Detailed information on how to take Lorcaserin is contained in the instructions for use included with the drug:
- single dosage - 10 mg (= 1 tablet);
- twice a day - morning and evening;
- the interval between each dose should be at least 12 hours, so you need to take it strictly at the same time (for example, at 07.00 and 19.00; or 08.00 and 20.00, etc.);
- The use of the drug does not depend on food intake: the tablet can be taken before, after, and during meals.
The course of treatment is until the desired result is achieved.
If within 3 months after starting treatment, the weight either has not changed, or has increased, or decreased, but no more than 5% of the original, the drug should be discontinued.
Interaction with other drugs
It is not recommended to combine Lorcaserin with the following medications:
- Products for hyperactivity and reduction of attention deficit disorder,
- Drugs to improve potency,
- Means for stabilizing blood pressure,
- Insulin,
- Psychotropic products,
- Antidepressants.
Lorcaserin should also not be used together with Dostinex, Tryptophan, Dextromethorphan.
Analogs
Lorcaserin has analogues:
- Denfluramine,
- Sibutramine,
- Dexefenfluramine,
- Fluoxetine and others.
All these drugs have similar actions - they affect the area of the central nervous system responsible for satiety of the body and the feeling of hunger. However, Lorcaserin has an advantage over other products.
The drug has a delayed effect, that is, appetite does not return to its previous state even after stopping taking the drug.
Compound
In addition to the main active ingredient, tablets and capsules may contain additional components:
- microcrystalline cellulose;
- mannitol;
- hydro- and hypromellose;
- ethylcellulose dispersion;
- colloidal silicon dioxide;
- polyethylene glycol;
- titanium dioxide;
- talc;
- iron oxide;
- Magnesium stearate.
The content of additional components is a minimal percentage and does not have a negative effect on health.
Where can I buy?
Lorcaserin is not sold in Russia. Therefore, it is not possible to buy the drug in pharmacies.
The drug is sold in the USA in pharmacies, but only with a doctor's prescription. According to the laws of this country, the resale and transfer of this product is illegal. For this reason, anyone who purchases this product on websites over the Internet must understand that there is a high risk of buying a counterfeit, and also that he is committing an illegal act.
At the time of buying
If we summarize all the reviews, it turns out that the product is very good. It is often taken not only by women fixated on a beautiful figure, but also by men who are aware of their problem of excess weight. It may not always be possible to achieve an amazing effect, but even a small result at the first stage of losing weight will be pleasant.
So, if someone who is losing weight decides to purchase Lorcaserin, the price will not be the least of their interests. Can a person with average income afford the drug or is the purchase only for the powers that be? And wouldn’t purchasing the product be a loss of money, not kilograms? In Russian pharmacies, the price for a package is 900 rubles, which is quite significant for the average worker. Buying from online pharmacies will be more profitable, but is it wise to buy Lorcaserin? The price, according to consumers, is justified. One package is enough for an entire course of treatment, that is, for the time when the first effect should appear.
Reviews from experts
Experts have left reviews about the drug Lorcaserin.
Svetlana Borisovna, nutritionist, work experience of more than 10 years “As an experienced nutritionist, I can say with confidence that there is no remedy that will help you get rid of excess weight quickly and without effort on the part of someone losing weight. There are medications that can help you lose weight if you follow a diet and increase physical activity. One of them is Lorcaserin. The manufacturer does not promise users instant weight loss, but talks about the effect on the central nervous system centers responsible for the feeling of hunger and fullness of the body. This makes it easier to endure the diet without breaking down a few days after starting it. However, I do not recommend taking the drug to everyone. The product has both contraindications and side effects, which I always take into account before recommending taking the product. In most cases, the product gives a positive effect, but only in conjunction with diet and exercise and following the instructions for using the drug."
Path of the drug to the audience
When first applied for mass production, the weight loss drug was not approved. The reason was a number of side effects, including the development of tumors and heart failure. Upon re-application, additional information about the drug was provided. Manufacturers indicated the percentage of probability (extremely low) of the disease, which convinced experts to give permission for registration. The instructions for the drug indicated the following side effects: depression, memory loss, migraine, arterial hypertension. Possible side effects, when compared with the expected benefits, turn out to be insignificant, especially considering that there is a real obesity epidemic in America, and citizens need help.
Reviews of those losing weight
There are also reviews of the drug Lorcaserin from those losing weight.
Marina, 37 years old “I have never resorted to drugs to lose weight, although I had to go on diets quite often. I can't keep the weight off. Pastries and cakes are my weakness. Usually a small piece is enough for me to enjoy, but not to overeat. However, when stress happens, I start using everything indiscriminately and cannot stop. Because of this, I gain weight and have to go on a diet again. After another diet, I noticed that my skin could no longer cope with such a pace and began to sag. That’s why I decided to use a weight loss product, but one that would suppress the feeling of hunger and allow me to quickly feel full. This drug was Lorcaserin, so I ordered it. I took the drug for a year. At first I had problems with my intestines, but it turned out that this was not because of the drug, but because I began to eat less. During this time I lost 35 kg, but that’s not the main thing. I started eating less, so the extra pounds are no longer coming back.”
Maria, 41 years old “I took the drug Lorcaserin on the recommendation of a nutritionist. I wanted to lose weight quickly, but the specialist said that it was harmful to health and did not give lasting results. It’s better to gradually change your diet, which will help you lose weight. According to the doctor, Lorcaserin was supposed to help me tolerate changes in the nutritional system more easily and not give up on my intended goal due to constant hunger. I started taking the product and after a week I realized that I had given up snacking. I started to eat up very quickly. One small portion was enough to fill me up. So gradually I changed my diet and as a result I was able to lose weight from 92 to 57 kg.”
Alexandra, 37 years old “Before my second birth, I had no problems with excess weight. After the birth of her first daughter, she quickly got into shape. I didn’t even have to resort to diets or trainers. It was enough to take care of the child and the house, and take care of the garden beds in the summer. I thought that after the birth of my second daughter there would be no problems, but I was wrong. There was no way I could return to my previous diet. The hunger was so strong that we constantly had to make ourselves sandwiches. This led to me gaining even more weight after giving birth. When I finished breastfeeding, I immediately ordered Lorcaserin, because I read that the drug dulls hunger and allows the body to quickly become full. Tala took the pills and everything happened as the manufacturer stated. I began to fill myself up, eating only half the portion. Plus I gave up snacking. This helped me, within a year, completely lose the weight that I had gained before pregnancy and during lactation, that is, from 29 kg. After stopping taking the drug, I did not return to my old diet, so the weight did not return.”
About the sale
Lorcaserin is not registered in Russia, therefore distribution is prohibited throughout the Russian Federation. You cannot buy the drug, even if by some miracle you have a prescription on hand.
Experts predict that very soon Lorcaserin manufacturers will be able to obtain a license for sale in Russia (after completing all the required procedures). But exactly when this will happen is unknown. Considering the psychotropic effect of the drug, it is assumed that, as in the USA, it will be prescribed exclusively by a doctor, and dispensed in pharmacies strictly according to prescriptions.
Today, there are two ways to purchase Lorcaserin.
The first is to order from one of the online stores. There are resources offering to buy the drug for only $50 (60 capsules). At the same time, you need to keep in mind that any import into Russia (carried out by you personally or by courier - it doesn’t matter) is unauthorized and involves punishment at the legislative level. Therefore, you should think carefully before clicking the order button. Moreover, in most cases such resources sell counterfeits, because sellers probably know about the ban on Lorcaserin in the Russian Federation.
The second way is to purchase abroad. In Germany and Israel, a jar of 60 tablets will cost $245, in the USA - $100. Even if you compare these prices with those offered in online stores, doubts will creep in about the quality and authenticity of the latter. Purchasing in the above countries will be completely legal. But again, you will have to take Lorcaserin outside of Russia, since import into the country is prohibited.
