Goldline plus caps 10mg+158.5mg N90 (Izvarino)

To get rid of excess weight and leave health problems caused by excess kilograms in the past, it makes sense to use modern effective drugs. Fortunately, there are a huge number of them on the market. When choosing among this variety, it makes sense to first study how the manufacturer recommends using the product he has developed, and get acquainted with the opinions of those who have already tried it. So, the instructions and reviews for Goldline Plus are the very necessary minimum of information that allows you to decide in favor of this medication or decide that it is completely unsuitable.

What is it about?

The main components of the medicine for losing excess weight are cellulose in the form of microscopic crystals and sibutramine. It is sibutramine that has the desired effect - it helps to lose weight. There are two dosage options for the active component; accordingly, there are two forms of Goldline Plus tablets on sale (the instructions for use are the same for them): 10 mg, 15 mg.

The product belongs to the combined category. Sibutramine is known for its pronounced effect when used, which forces one to treat the substance very carefully. However, combined with cellulose, presented in the form of microscopic crystals for greater efficiency, it becomes, although an effective compound, but without specific restrictions on use. Due to the peculiarities of its composition, the drug “Goldline Plus” (instructions are always included with the tablets) is not classified as a potent medicine. To purchase the product at a pharmacy, it is enough to present a prescription from the attending physician, written out according to Form 107. Some pharmacies sell the drug freely without a prescription.

Analogues of the drug

If for some reason it is impossible to take Goldline Plus, then it is recommended to use a similar remedy to get rid of excess weight.

The most popular substitute, similar to it in composition and mechanism of action, is Reduxin . It is considered the “twin” drug to Goldline Plus. Its main active ingredient is sibutramine. It also contains cellulose in microcrystals. It causes a feeling of fullness with less food consumption, while maintaining it for a long time, blocks the feeling of hunger.

The difference in the drugs is the dose of active ingredients. The cost of Reduxin is on average 3 times more than Goldine Plus.

How it works?

The composition of Goldline Plus is fully described in the instructions, and the mechanism of pharmacological effectiveness of the drug is also given here. As mentioned above, the main active ingredient is sibutramine. Both this active component and the products of its metabolism strongly influence the processes occurring in the synaptic cleft. This primarily affects serotonin and norepinephrine, which are classified as neurotransmitters.

This effect on neurotransmitters provides a long-lasting feeling of satiety, that is, the feeling of hunger becomes weak and disappears altogether. At the same time (and this is evidenced by reviews of those losing weight, instructions for “Goldline Plus”), heat production increases, as thermogenesis is activated.

Theory and practice

The theoretical explanation of the effectiveness of medications is good, but only because the effectiveness of its use is confirmed by practical research. The manufacturer has organized a fairly wide variety of clinical trials designed to prove the good effect of regular use of the developed medication. Practice has proven that when you follow the instructions for using Goldline Plus tablets, sibutramine has a very strong effect. Almost immediately, the amount of food consumed drops by 20%. The calorie content of the diet is reduced by a quarter.

An additional effect on the figure is provided by the activation of thermogenesis, which requires about 100 kcal per day. Regular intake in accordance with the instructions for use of Goldline Plus 15 mg ensures the growth of high-density triglycerides. At the same time, the concentration of cholesterol, low-density lipoproteins, and triglycerides is reduced. In addition, the level of uric acid presence decreases.

Effective and safe

From the instructions and description of “Goldline Plus” it follows that the main effective component present in the medication does not have a narcotic effect, it does not become addictive even with long-term use of the drug.

Cellulose, present in the form of microscopic crystals, is an effective enterosorbent. It has all the positive qualities of a classic sorbent, at the same time it fights poisoning of the body of a non-specific nature, helping to remove toxins. As indicated in the instructions for Goldline Plus (15 mg), cellulose can bind microorganisms, which simplifies their removal from the human body. In this way, waste products of microscopic life and poisonous components of various origins (endogenous, exogenous) are also removed. Cellulose binds well and eliminates allergy-provoking substances, xenobiotics, and metabolic products formed in an excessively large volume. From the instructions for “Goldline Plus” (15 mg) it follows that it is thanks to cellulose that taking the drug allows you to get rid of the products of the metabolic process that provoke endogenous toxicosis.

When is it possible?

From the reviews and instructions for use of Goldline Plus, it is clear when the product is allowed to be taken, when its use has a truly significant result. If we summarize all the indications briefly, we get the following list:

• obesity;
• excess weight, accompanied by additional health problems.

Obesity is diagnosed when the body mass index (BMI) reaches 30 kg/m2.

Excess weight that requires correction begins with a BMI of 27 kg/m2, if a person is sick with any serious illnesses. Most often it is type 2 diabetes and high blood pressure.

Instructions for use

The product is not a dietary supplement or an addictive psychotropic substance. Dispensed with a doctor's prescription. Self-appointment is unacceptable. The doctor must supervise the therapeutic process.

In addition to mandatory daily intake, nutritional correction and increased physical activity are necessary.

The capsule is taken in the first half of the day 30 minutes before meals, washed down with plenty of water.

Depending on the task and initial indicators, the duration of the course is determined individually. The maximum duration of treatment is 2 years.

If after 3 months the loss of body weight is less than 5% of the initial weight, then you should stop using the medication and consult a doctor for treatment adjustments.

The average price in Russia is 1061 – 3720 rubles.

How to use?

Proper use is described in detail in the instructions for use of Goldline Plus (15 mg). In the classic version, you need to drink one capsule per day. Reception time is morning, before noon. When therapy is just starting, it is enough to take 10 mg at a time. Conclusions about the effectiveness of the medication are made 4 weeks from the start of treatment.

If by the control point your body weight has not decreased by at least 2 kilograms, you need to switch to a larger dose - 15 mg. The instructions for use of Goldline Plus categorically prohibit starting immediately with this concentration.

Directions for use and doses

Treatment begins with a lower dosage of sibutramine – 10 mg. The drug is taken once a day in the first half of the day, both on an empty stomach and with meals. If during the first month of use the loss of body weight does not exceed 2 kg, switch to a higher dosage of 15 mg.

The effect of the drug develops gradually, the maximum effect is observed after three months of continuous use. It has been shown that taking the drug for six months makes it possible not only to reduce body weight, but also to form correct eating habits. It has been established that after discontinuation of the drug, the partial effect persists for up to two years.

The drug is not recommended for use for more than 1 year, since there is no clinical data on the effectiveness and safety of taking the drug for a longer period.

If after three months of use the reduction in body weight does not exceed 5% of the initial value, then the drug should be discontinued.

Slowly but surely

The instructions and reviews of the results of “Goldline Plus” state the same thing: it is pointless to expect an immediate effect from taking the medication, it will not happen. The remedy gradually has an increasingly stronger effect. The accumulation of the main active substance in the body occurs throughout the first month of treatment, and the effectiveness gradually becomes greater day by day. The effect of greatest strength can be recorded three months after the start of treatment, if you strictly follow the instructions for use of Goldline Plus and do not skip days.

The manufacturer warns: if for some unknown reason a day falls out and the prescribed capsule is not used, you do not need to take a double dose the next day. It is enough to simply leave the pass and extend the course for another day. At the same time, you need to understand that a large number of such absences may call into question the effectiveness of the entire treatment program as a whole. The manufacturer in the instructions for Goldline Plus calls for attentiveness and accuracy.

Whether long or short...

The average duration of the course is six months. It is believed that during this period it is possible to get rid of extra pounds, as well as develop eating habits that allow you to maintain your figure in the future, without the help of medication. The instructions for Goldline Plus mention that, to some extent, the effectiveness of the drug is felt even two years after completion of the course of treatment.

The manufacturer recommends completing the course no later than one year from the start of therapy. There is no definitive information about whether taking longer periods of time is effective, and there is no official data on the safety of such treatment.

What if I don't like it?

In rare cases, obese patients do not tolerate the medication in question well. In addition, there are cases where, based on the results of a full three-month course, weight loss was 5% or less. In such a situation, as follows from the instructions for Goldline Plus, you should stop therapy and stop taking the medication.

The manufacturer points out that truly high efficiency can be achieved if you approach the task comprehensively. This requires paying special attention to the quality of nutrition, choosing low-calorie foods whenever possible and eating them in reasonable quantities. In addition, from the instructions for “Goldline Plus” it follows that the greatest results can be achieved by combining drug therapy and an active life rich in physical activity.

Negative effects

Both the instructions for Goldline Plus and the doctors prescribing this drug warn about the possibility of side effects. It is known that negative manifestations are more typical in the first month, when the body adapts to taking the medication and a slight restructuring occurs. However, all known side effects are mild and do not require adjustment of the dose or dosage regimen, or the use of additional tablets. After a month, all side effects, as the instructions for Goldline Plus assure, will go away on their own without a trace.

Most often, patients encounter the following negative phenomena:

• sleep disorders;
• headache;
• dries out the mouth;
• dizzy;
• tachycardia;
• blood pressure rises;
• loss of appetite;
• nauseated;
• problems with stool;
• feeling restless;
• The activity of the sweat glands increases.

Side effects

Most often, side effects occur at the beginning of treatment (in the first 4 weeks). Their severity and frequency weaken over time. Side effects are generally mild and reversible.

Very common side effects are dry mouth and insomnia, and headache, dizziness, restlessness, paresthesia, and changes in taste are common. Tachycardia and palpitations are common. There is a moderate increase in heart rate by 3-7 beats per minute. In some cases, a more pronounced increase in heart rate cannot be ruled out. Clinically significant changes in pulse are recorded mainly at the beginning of treatment (in the first 4-8 weeks).

Vascular disorders: increased blood pressure and vasodilation are common. There is a moderate rise in blood pressure at rest by 1-3 mmHg. Art. In some cases, more pronounced increases in blood pressure cannot be ruled out. Clinically significant changes in blood pressure are recorded mainly at the beginning of treatment (in the first 4-8 weeks).

Gastrointestinal disorders: loss of appetite and constipation are very common, often nausea and exacerbation of hemorrhoids. If you are prone to constipation in the first days, monitoring the evacuation function of the intestines is necessary. If constipation occurs, stop taking it and take a laxative.

Skin and subcutaneous tissue disorders: increased sweating is common.

You can’t - that’s all!

There are a number of contraindications that completely prohibit the use of the Goldline Plus medication or impose serious restrictions, non-compliance with which can be dangerous to the health and even life of the patient. There are relatively few contraindications, but it is important to be careful. All of them are listed in the instructions for the drug, and it is recommended to further study the list before starting regular use of the tablets.

The product should not be used if:

• obesity caused by organic causes;
• intolerance to the components of the medication, especially sibutramine;
• bulimia, anorexia;
• mental disorders;
• Gilles de la Tourette's disease.

It is not allowed to simultaneously carry out therapy with MAO inhibitors and Goldline Plus.

If diseases of the heart and blood vessels are known, you need to carefully study the anamnesis, and only then prescribe the remedy. Treatment is not allowed if angina pectoris, heart attack, tachycardia or arrhythmia are established. Very strict restrictions are set by heart failure and disturbances in the activity of occlusive arteries. You cannot resort to the use of Goldline Plus if cerebrovascular pathologies or uncontrollable hypertension are diagnosed.

Contraindications

• Known hypersensitivity to sibutramine or other components of the drug;
• The presence of organic causes of obesity (for example, hypothyroidism);
• Serious eating disorders - anorexia nervosa or bulimia nervosa;
• Mental illnesses;
• Gilles de la Tourette syndrome (generalized tics);
• Concomitant use of MAO inhibitors (for example, phentermine, fenfluramine, dexfenfluramine, ethylamphetamine, ephedrine) or use within 2 weeks before taking the drug Goldline® PLUS and 2 weeks after the end of its use of other drugs acting on the central nervous system, inhibiting serotonin reuptake (eg, antidepressants, antipsychotics); sleeping pills containing tryptophan, as well as other centrally acting drugs for weight loss or for the treatment of mental disorders;
• Cardiovascular diseases (history or current): coronary heart disease (myocardial infarction (MI), angina); chronic heart failure in the stage of decompensation, occlusive diseases of peripheral arteries, tachycardia, arrhythmia, cerebrovascular diseases (stroke, transient cerebrovascular accidents);
• Uncontrolled arterial hypertension (blood pressure (BP) above 145/90 mm Hg) (see also section “Special instructions”);
• Angle-closure glaucoma;
• Thyrotoxicosis;
• Severe liver and/or kidney dysfunction;
• Benign prostatic hyperplasia;
• Pheochromocytoma;
• Established pharmacological, drug or alcohol dependence;
• Pregnancy and breastfeeding period;
• Age under 18 and over 65 years.

Restrictions: when else is it not allowed?

Taking Goldline Plus is not possible if you have the following health conditions:

• glaucoma;
• problems with the liver, kidneys;
• prostatic hyperplasia;
• dependence on alcohol, drugs, medications;
• thyrotoxicosis;
• pheochromocytoma.

The manufacturer sets age limits for the use of Goldline Plus: 18-65 years. It is strictly unacceptable for minors and the elderly to use the medication. It should also not be used during pregnancy or lactation. No clinical trials have been conducted to determine the effect of the drug on the fetus and the ability to penetrate into breast milk, so the manufacturer cannot be held responsible for the consequences. It is also unknown how maternal use of the drug may affect a breastfed infant.

Side effects and contraindications

Like any medical product, Goldline Plus has restrictions on its use. This list includes:

• pregnancy, breastfeeding period;
• age categories up to 18 and after 65 years.
• cardiovascular diseases;
• renal or liver failure;
• mental disorders;
• glaucoma;
• pathologies of the circulatory system;
• organic obesity;
• anorexia or bulimia associated with psychological disorders.

Before taking, you should carefully read this list. If you experience at least one of the points presented above, then you should stop using this product. Otherwise, this can lead to serious health problems.

While taking Goldline plus, negative consequences may occur:

• nausea;
• dizziness;
• heart rhythm disturbance;
• insomnia;
• dry mouth;
• stomach upset.

It is noted that such symptoms most often occur in the first month of use. If the nature of the phenomenon is not pronounced, then adjustment of the dose or the entire regimen is not required. This indicates the body’s adaptation to the drug and new lifestyle.

If after 4 weeks the negative phenomena do not go away or take on a different character, then you should immediately stop therapy and consult a specialist. You may need to change your dosage or stop taking the drug completely.

Excess in the body: how is it expressed?

It is known that if Goldline Plus is taken carelessly, an overdose is possible. Information about this phenomenon, as indicated in the instructions for the medication, is quite limited. Typical manifestations of an excess of active components of the drug in the body:

• heart rhythm disturbance;
• headache;
• high blood pressure.

It is also known that dizziness is likely.

There are no special antidotes; the situation does not require specific treatment. The manufacturer indicates that when such a condition is reached, completely stop using the medication and notify the attending physician about the current situation. Based on the information received from the patient and the results of laboratory tests, the doctor makes a decision on how to continue treating the patient. It is unacceptable to adjust treatment at your own discretion.

Side effects of Goldline

Especially at the beginning of treatment, Goldline can cause side effects and cause problems with the central nervous system and brain. They cannot lead to serious consequences, but they will cause at least a lot of discomfort, so when taking the medicine it is important to monitor possible symptoms:

• Feeling of restlessness, anxiety
• Increased heart rate
• Dizziness and headache
• Nausea, severe dry mouth
• Constipation
• Increased nervousness, sleep disturbance
• High blood pressure, increased heart rate
• Fatigue, sweating
• Swelling, redness and itching of the skin

In case of an overdose, similar signs may also appear. If they are detected, you should drink activated carbon, provide yourself with access to fresh air and call a doctor.

Features of use

If for some reason it is not possible to use Goldline Plus, you can replace it with Reduxin. In terms of its composition, this medication is a complete analogue of the described drug. On average, the cost of Goldline Plus in apexes is from 500 rubles per package. The analogue is much more expensive, the cost of “Reduxin” is about one and a half thousand in prices for the current year. If you believe the reviews about the effectiveness of the drug, the results of taking these two drugs are almost identical, despite such a large difference in cost.

The manufacturer recommends using Goldline Plus if the patient has already made attempts to lose weight without pharmacological help, but all of them were unsuccessful, that is, in three months the weight loss was within five kilograms. Many doctors, recommending the use of Goldline Plus, note that you can immediately begin treatment by combining medication and the right diet. The fact is that the drug reduces appetite, and the need to limit oneself in food is much easier for a person. Correct use of medical care allows you, without harm to yourself, without suffering and hunger strikes, to form correct eating habits that can be followed after the completion of specific therapy.

Goldline price

At a dosage of 15 mg, the average price for the drug in pharmacies is:

• 1500 rubles for 30 tablets
• 2500 rubles for 60 tablets
• 3500 rubles for 90 tablets (course for 3 months)

A more expensive analogue of the drug Goldline is known as Reduxin and has a price that is almost 2 times higher than Goldline - from 3 thousand to 7 thousand rubles per package. The light version of Goldline has a more affordable price - about 1,300 rubles for a three-month course.

If you monitor your health, do not exceed the prescribed dosage of the drug, engage in moderate physical activity, follow your doctor’s recommendations and fully follow the instructions, with the help of Goldline capsules you can easily get rid of extra pounds without effort or harm to your health.

We produce and sell: everything is original

Goldline Plus is produced by a Russian pharmaceutical company, which explains such an affordable price for a package of medicine. The manufacturer knows the needs and capabilities of the domestic buyer and produces the product that people need.

An effective and efficient drug is available in Russian pharmacies without a prescription, although use without supervision by a physician is strictly not recommended. The ratio of quality, cost, availability, assures the optimal. Should you believe this? Reviews of people who have already undergone treatment and lost excess weight can tell you about this.

What are people saying?

There are quite a lot of reviews about Goldline Plus on the Russian-language sector of the Internet. This is not surprising, because the problem of excess weight has worried a very large number of people in recent years, and this remedy, according to the manufacturer’s assurances, allows you to solve them quickly, effectively, and even at a low cost per package. Many people argue according to the principle: it’s inexpensive - why not try it.

However, this approach has certain negative aspects. As practice shows, people often prescribe Goldline Plus to themselves, do not consult a doctor and do not undergo any special examinations, including for the presence of contraindications and intolerance. This causes allergic reactions and side effects. Of course, such negative practice only leaves a bad impression.

Another subtle point is the importance of an integrated approach. Maximum effectiveness of taking Goldline Plus can be achieved if at the same time you switch to a balanced diet with a low calorie content and regularly give yourself physical activity. Those who want to lose weight, who relied only on pharmacological help without any special participation on the part of the person losing weight, practically did not achieve good results. There are exceptions, but they are quite rare.

Are there any satisfied ones?

It should be noted that most of the reviews on the Russian-language Internet about Goldline Plus are positive. Those who took it for the purpose of losing weight noted that in just a month they managed to lose up to ten kilograms. What is important is that such feedback about the effectiveness of the product comes not only from people who suffer from a very large number of extra pounds, but also from those who have relatively little excess weight.

Patients who have lost weight with Goldline Plus agree that the product is easy to use, and side effects, although almost always present, are quite mild, so they can be ignored. If we compare the negative impressions of side effects with the effectiveness of the course, then the questions disappear by themselves, it is clear that “the game is worth the candle.”

What should you be prepared for?

Of the negative effects, those who took Goldline Plus as a course most often noted dizziness and dry mouth. Many also had problems sleeping at first, but by the end of the first month of treatment (as the manufacturer assures), the negative effects completely disappeared. Some also mention the cost of the medication among the negative qualities, but compared to the prices of alternative options for weight loss, especially the full analogue of Reduxin, the price looks more than affordable.

Particularly trustworthy are the reviews of those who have been losing weight for quite a long time, in different ways and methods. Many note that most of the widely advertised products are either ineffective or cause too many side effects, so choosing Goldline Plus becomes the optimal solution. If you believe the reviews, with the help of Goldline Plus, even those who have almost come to terms with the impossibility of losing weight to the desired state have gotten rid of excess weight. People note that the effect of taking the medication lasts for a long time. The manufacturer explains this by developing correct eating habits during the course. Of course, ordinary people do not use such official terms, but they immediately see the result - even six months after completion of treatment, the weight still remains within the desired range.

Goldline plus caps 10mg+158.5mg N90 (Izvarino)

Goldline® PLUS should be used only in cases where all non-drug measures for weight loss are ineffective - if the weight loss over 3 months is less than 5 kg. Treatment with Goldline® PLUS should be carried out as part of complex weight loss therapy under the supervision of a physician with practical experience in the treatment of obesity. Complex therapy includes both changing diet and lifestyle, as well as increasing physical activity. An important component of therapy is to create the prerequisites for persistent changes in eating behavior and lifestyle, which are necessary to maintain the achieved weight loss even after drug therapy is discontinued. As part of treatment with Goldline® PLUS, patients need to change their lifestyle and habits in such a way as to ensure that the achieved weight loss is maintained after completion of treatment. Patients should be clear that failure to comply with these requirements will lead to repeated weight gain and repeated visits to their doctor. Patients taking Goldline® PLUS should have their blood pressure and heart rate measured regularly. During the first 3 months of treatment, these parameters should be monitored every 2 weeks and then monthly. If during two consecutive visits an increase in resting heart rate >\000910 beats per minute or systolic/diastolic pressure > 10 mm Hg is detected. Art., it is necessary to stop treatment. In patients with arterial hypertension whose blood pressure is above 145/90 mm Hg during antihypertensive therapy. Art., this control should be carried out especially carefully and, if necessary, at shorter intervals. In patients whose blood pressure exceeded 145/90 mmHg twice during repeated measurements. Art., treatment with Goldline® PLUS should be discontinued (see section “Side Effects”). In patients with sleep apnea, blood pressure must be monitored especially carefully. The simultaneous administration of drugs that increase the QT interval requires special attention. These drugs include Hi-histamine blockers (astemizole, terfenadine); antiarrhythmic drugs that increase the QT interval (amiodarone, quinidine, flecainide, mexiletine, propafenone, sotalol); gastrointestinal motility stimulator cisapride; pimozide, sertindole and tricyclic antidepressants. This also applies to conditions that can lead to an increase in the QT interval, such as hypokalemia and hypomagnesemia (see also section “Interaction with other drugs”). The interval between taking MAO inhibitors (including furazolidone, procarbazine, selegiline) and Goldline® PLUS should be at least 2 weeks. Although a connection has not been established between taking sibutramine and the development of primary pulmonary hypertension, however, given the well-known risk of drugs in this group, with regular medical monitoring it is necessary to pay special attention to symptoms such as progressive dyspnea (breathing difficulty), chest pain and swelling in the legs . If you miss a dose of Goldline® PLUS, you should not take a double dose of the drug at the next dose; it is recommended to continue taking the drug according to the prescribed regimen. The duration of taking Goldline® PLUS should not exceed 1 year. When taking sibutramine and other serotonin reuptake inhibitors together, there is an increased risk of bleeding. In patients predisposed to bleeding or taking drugs that affect hemostasis or platelet function, sibutramine should be used with caution. Although there is no clinical evidence of addiction to sibutramine, the patient's history of drug dependence should be assessed and attention should be paid to possible signs of drug abuse. Effect on the ability to drive vehicles and machinery Taking Goldline® PLUS may limit the ability to drive vehicles and machinery. During the period of use of the drug Goldline® PLUS, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Summing up

“Goldline Plus” is effective due to the microscopic crystals of cellulose and the active substance sibutramine it contains. The latter affects the human brain, in particular, the areas responsible for the feeling of hunger, due to which the patient quickly becomes full and wants to eat less often. The feeling of hunger is suppressed, but satiety, on the contrary, persists for a long time. Correct use of Goldline Plus allows you to reduce the amount of food consumed. With a correctly selected diet, you can provide the body with all the necessary components, microelements, and vitamins for full functioning with much smaller amounts of food, that is, losing weight with the help of medication will not cause harm to health. However, it is recommended to select nutrition under the supervision of a nutritionist.

Cellulose allows you to remove toxins, poisons, and breakdown products from the body that negatively affect internal organs and systems. This is a powerful and effective sorbent, completely safe for humans.

The medicine is commercially available in capsules in dosages of 10 and 15 mg. Each capsule, regardless of the amount of sibutramine, contains 158 g of cellulose. The capsules are hard, covered with a gelatin shell, have a white body with a blue cap, and are filled with white powder. The medication is packaged in a cardboard package containing contour packs of 10 or 15 capsules.

Pharmacological properties

The action of Goldline Plus is determined by its constituent components. Sibutramine is a prodrug that is converted in the body into metabolites - primary and secondary amines, which exert a therapeutic effect - block the reuptake of neurotransmitters - serotonin, norepinephrine, dopamine - in the synaptic cleft. Due to this, the feeling of satiety is prolonged, the feeling of hunger is reduced and heat production is increased.

Clinical studies have shown that reducing the feeling of hunger and prolonging the feeling of fullness leads to a reduction in the volume of food consumed by 20% and caloric intake by 25%. Due to the increase in heat production, about 100 kcal are burned additionally per day.

While taking Goldline Plus, in addition to reducing body weight, there is an increase in the blood level of high-density lipoproteins (HDL), a decrease in low-density lipoproteins (LDL), total cholesterol, triglycerides and uric acid.

Microcrystalline cellulose (MCC) is an enterosorbent, has a nonspecific detoxification and sorbent effect, binds and removes from the body various microorganisms, their metabolic products, allergens, xenobiotics, toxins of endogenous and exogenous nature.