Orlistat-Akrikhin. Reviews of those losing weight, instructions for use

What's in the article:

1. Orlistat: instructions for use
2. Orlistat: reviews, impressions

The problem of excess weight worries a huge number of the country's adult population.

Today on the weight loss portal “Lose Weight Without Problems” we will discuss the popular drug Orlistat, the reviews of which are very different. But first, let’s figure out what this remedy is, which some consider a panacea, while others consider it an absolute evil.

Let us immediately note that Orlistat is not a food supplement, but a real medicine that can only be purchased with a doctor’s prescription.

At its core, it is a lipase inhibitor. When taken orally, the drug inhibits pancreatic and gastric lipases, as a result of which the breakdown of fats is disrupted. Thanks to this, they are absorbed from the gastrointestinal tract with much less intensity, and this leads to weight loss.

Indications for use

Orlistat-Akrikhin - (reviews of people losing weight with the drug are given below in the article) a drug used to reduce excess weight in people suffering from overweight and obesity. Medical indications for prescribing the drug are considered to be BMI values ​​≥29 kg/sq. m — ≥30 kg/sq. m.

The use of the drug is recommended, including for persons whose weight gain was accompanied by diseases associated with obesity:

• insulin-dependent diabetes mellitus (type 2);
• dyslipidemia;
• elevated blood pressure levels.

Orlistat-Akrikhin helps fight excess weight.
It is possible to use the medication for faster weight loss while following a low-calorie diet. In this case, prior to independent use, a preliminary consultation with a doctor is recommended.

Orlistat: instructions for use

This medicine is prescribed, as a rule, to those for whom diets and various fitness activities are no longer able to help.

Orlistat, about which doctors have divided reviews, has a large list of possible side effects. The instructions warn that in some cases, “fatty stools,” flatulence, frequent bowel movements, oily discharge, fecal incontinence, and an imperative urge to defecate may occur.

In addition, some patient reviews characterize Orlistat as affecting the condition of teeth. Use the medicine in combination with diet.

It is not recommended to take the drug for pregnant and lactating women, or to combine it with other drugs.

You can find out how other diet pills act on the body on our website hudeem-bez-problem.ru.

Compound

Orlistat-Akrikhin (reviews of people losing weight with the help of the drug note faster weight loss that occurs under the influence of the drug on a low-calorie diet) is created on the basis of a water-insoluble white crystalline powder - orlistat.

Once in the body, crystals of the substance bind to gastric and pancreatic lipases, blocking their activity when breaking down fats entering the body with food, thereby artificially creating a calorie deficit.

Undigested fats are eliminated from the body, and hungry cells are forced to use fat accumulations previously accumulated in lysosomes for nutrition, thus provoking a decrease in body weight.

In addition to orlistat, the drug includes:

Listata

Pharmacodynamics

Orlistat is a potent, specific and reversible inhibitor of gastrointestinal lipases with a long-lasting effect. Its therapeutic effect occurs in the lumen of the stomach and small intestine and consists of the formation of a covalent bond with the active serine site of gastric and pancreatic lipases.

The inactivated enzyme then loses the ability to break down food fats, which come in the form of triglycerides, into absorbable free fatty acids and monoglycerides. Since unsplit triglycerides are not absorbed, the resulting decrease in caloric intake into the body leads to a decrease in body weight. Thus, the therapeutic effect of the drug is carried out without absorption into the systemic circulation.

Based on fecal fat results, the effects of orlistat begin 24 to 48 hours after dosing. After discontinuation of orlistat, fecal fat content usually returns to pre-therapy levels within 48-72 hours.

Clinical effectiveness

Patients taking orlistat experience greater weight loss compared to patients on diet therapy. Body weight loss begins within the first 2 weeks after the start of treatment and continues from 6 to 12 months, even in patients with a negative response to diet therapy. Over the course of 2 years, there was a statistically significant improvement in the profile of metabolic risk factors associated with obesity. In addition, compared to placebo, there was a significant reduction in body fat. Orlistat is effective in preventing weight gain. Re-gain of body weight, no more than 25% of lost, is observed in approximately half of the patients, and in half of these patients, re-gain of body weight is not observed or even a further decrease is observed.

Overweight or obese patients with type 2 diabetes mellitus treated with orlistat for 6 months to 1 year experienced greater weight loss compared with patients receiving dietary therapy alone. Weight loss occurs mainly due to a decrease in the amount of fat in the body. With orlistat therapy, a statistically and clinically significant improvement in glycemic control is observed. In addition, during therapy with orlistat, there is a decrease in the dose of hypoglycemic agents, insulin concentration, as well as a decrease in insulin resistance.

When using orlistat for 4 years, the risk of developing type 2 diabetes mellitus is significantly reduced (by approximately 37% compared to placebo). The degree of risk reduction is even greater in patients with baseline impaired glucose tolerance (approximately 45%).

Maintaining body weight at a new level is observed throughout the entire period of use of the drug.

When orlistat was used for 1 year in obese adolescents, there was a decrease in BMI, a decrease in fat mass, and a decrease in waist and hip circumference compared to the placebo group. Also, patients treated with orlistat showed a significant decrease in diastolic blood pressure compared to the placebo group.

Pharmacokinetics

Suction

In normal weight and obese volunteers, systemic exposure to orlistat is minimal. After a single oral dose of 360 mg, unchanged orlistat is undetectable in plasma, which means that its concentrations are below the limit of quantitation (less than 5 ng/ml).

In general, after taking therapeutic doses, it was possible to detect unchanged orlistat in blood plasma only in rare cases, and its concentrations were extremely low (less than 10 ng/ml or 0.02 μmol). There are no signs of accumulation, which confirms that the absorption of orlistat is minimal.

Distribution

Vd cannot be determined because orlistat is very poorly absorbed. In vitro, orlistat is more than 99% bound to plasma proteins (mainly lipoproteins and albumin). In minimal quantities, orlistat can penetrate red blood cells.

Metabolism

Orlistat is metabolized primarily in the intestinal wall. In obese patients, approximately 42% of the minimal fraction of orlistat that is absorbed systemically is accounted for by two main metabolites - M1 (a four-membered hydrolyzed lactone ring) and M3 (M1 with a cleaved N-formylleucine residue).

Molecules M1 and M3 have an open b-lactone ring and inhibit lipase extremely weakly (1000 and 2500 times weaker, respectively, than orlistat).

Given this low inhibitory activity and low plasma concentrations (average 26 ng/ml and 108 ng/ml, respectively) after therapeutic doses, these metabolites are considered pharmacologically inactive.

Removal

In individuals with normal and overweight, the main route of elimination is the elimination of unabsorbed orlistat through the intestines. About 97% of the dose taken is excreted through the intestines, with 83% as unchanged orlistat.

The cumulative renal excretion of all substances structurally related to orlistat is less than 2% of the administered dose. The time until orlistat is completely eliminated from the body (through the intestines and kidneys) is 3-5 days. The ratio of orlistat elimination routes in volunteers with normal and overweight was the same. Both orlistat and the metabolites M1 and M3 can be excreted in the bile.

Pharmacokinetics in special clinical groups

Plasma concentrations of orlistat and its metabolites (M1 and M3) in children do not differ from those in adults when comparing the same doses of orlistat. Daily excretion of fat in feces is 27% of dietary intake during orlistat therapy.

In what form is it produced?

Orlistat-Akrikhin (reviews of people losing weight recommend avoiding eating fatty foods while taking the drug, thereby preventing the occurrence of unpleasant side effects) are blue cylindrical capsules weighing 60 or 120 mg, packaged in blisters of 42 pieces.

The drug is distributed in lilac-white cardboard boxes. The cost of packaging is about 560 rubles.

Pharmadynamics

Once in the body, the drug, due to the crystalline powder orlistat it contains, blocks the enzymatic activity of intestinal and pancreatic lipases, thereby preventing the breakdown of fats that come with food.

Undigested particles are eliminated from the body through the intestines, forcing cells that have not received the necessary amount of energy to break down fat deposits accumulated in lysosomes to obtain nutrition. The blocking effect of orlistat does not affect the breakdown of protein and carbohydrate foods, slightly reducing the number of vitamins supplied with food.

Orlistat

20.05.18 11:26:24

Hello. By summer I decided to take care of myself. Go on a diet, start exercising. But how lazy it is, who would know. However, something needs to be done. I used to take a laxative drug, but it was not very beneficial for the body. The nutritionist, as usual, compiled a list of what you can’t eat (a whole list of almost all foods), and what you can eat—nothing. Funny. I went to the pharmacy to buy at least a set of “Turbo Slim”, but the pharmacist, such a pretty girl, said: “Try this product, Orlistat 60 mg, we are selling it.” I asked about its action, they explained to me that it removes fat from the body. I was overjoyed and daydreaming! I think I’ll buy it and try it, maybe it will help! I found out its price along the way, it seemed affordable - 625 rubles in total for the course. I bought it. Well, like a curious gopher, I sat down on the Internet to read, study reviews, and suddenly I bought it in vain? The reviews are different, some praise, some are dissatisfied, but since I bought it, I have to try it. With my weight of 78 kg at 160 cm, it certainly wouldn’t hurt to try it. So, I read the instructions, which said to take three times a day with meals, but no later than an hour after. I don't eat that much. I decided to save 42 tablets. Take two a day, just like I eat twice a day. I took it for three days, no side effects. I think, well, won’t it help me? I judge by side effects, but there are none. But in the evening it started. As prescribed - fatty stools, and other unpleasant fragments. I pulled myself together and limited myself to fatty foods, since the fat that was absorbed by me so deliciously, but not usefully, is removed. It seems like there are fewer problems, at least I’m no longer afraid to leave the house. Well, because fat stains laundry. Oh, worse than during the menstrual cycle! But, I’m stubborn, did I pay the money in vain? A week later I stepped on the scale - minus 600 grams! This has already made me happy. I started weighing myself every morning and discovered that on average I was losing 150 grams a day, no matter what I ate! And so, in 21 days I lost almost four kilograms and 74 kopecks simply amazed me! To celebrate, I bought shawarma with double cheese and away I went... My body rested for a month, I ate as usual, without these pills, especially trying to consume fatty vitamins, since Orlistat does not recognize the healthy or harmful fat we eat and removes absolutely all that was taken into the stomach. Therefore, it is still necessary to compensate for the lack of vitamins. When I weighed myself again, I realized that I had gained a little less than one and a half kg. Well, it's my own fault. You need to eat less. And yet, 75 and a half kg is better than 78 something. And I bought Orlistat again. In the same pharmacy, because for some reason it is more expensive in others. So, I’m thinking, where should I weigh myself? When they moved, the owners kept the scales. But I still feel that the fat is leaving my stomach and sides. As I understand it, having thrown out the absorbed fat from the body, the body begins to use the fat that was already deposited in the body for energy. That's the trick. At least I was able to fit into those breeches that for two years did not want to fit on my hips. This made me very happy and encouraged! Despite all the inconveniences associated with side effects, I bought another, already third, pack, although I have not drunk the second one yet. I will also drink in courses, take Orlistat for a month, rest for a month, although some in the reviews write that you can take it without a break for up to six months. Well, I don’t want to torture my body like that. Still, it needs healthy fat to function properly. My goal is to lose 56 kg to a normal weight. I hope I can do it this summer. In any case, I go for long walks once a week. And a contrast shower for skin tightening is said to help. This is my personal experience. There is an effect, I like it, despite the side effects.

Application

Orlistat-Akrikhin (reviews of people losing weight with the drug note the possibility of accelerated weight loss when combining the drug with an active lifestyle) must be taken without chewing and with plenty of water. The full course of treatment should not exceed 2 years.

For adults

For people who want to lose weight or who are obese, the drug is prescribed in a course of 3 capsules daily before or during meals. A single dose of the drug should not exceed 60-120 mg.

If the food does not contain fat, you can skip the medication.

You should not take more than 3 capsules per day, since increasing the dosage is not accompanied by an increase in the therapeutic effect.

For a faster effect, the Orlistat-Akrikhin course must be combined with a low-calorie diet and moderate sports training. Nutritionists also strongly advise reducing the amount of fatty and high-calorie foods consumed during treatment, thereby preventing the occurrence of unpleasant side effects of treatment.

The daily diet during therapy should include:

• a large variety of non-starchy vegetables and fruits;
• lean types of meat, poultry, fish;
• cereals;
• legumes;
• nuts and dried fruits;
• grain bread and bran.

During treatment, it is mandatory to adhere to a drinking regime, including at least 2 liters of daily fluid intake (mineral water, green tea, herbal decoctions). Any alcoholic beverages are completely excluded during treatment.

If no visible weight loss has occurred within 3 months of regular use of the drug, drug therapy should be stopped and additional studies should be prescribed. The total duration of taking Orlistat-Akrikhin should not exceed 2 years.

During pregnancy

While waiting for a child, taking the drug is strictly prohibited.

If it is necessary to treat a nursing mother, breastfeeding should be interrupted before prescribing the drug.

For the elderly

Laboratory tests have not been conducted on elderly people, so for those over 60 years of age, doctors can, if necessary, prescribe the usual dosage, consisting of 60 ml of the drug taken 3 times per day with each meal.

Orlistat-Akrikhin should not be prescribed for the treatment of excess weight caused by hormonal imbalances due to its low effectiveness.

Contraindications

It is prohibited to take the drug to persons:

• suffering from chronic digestive disorders;
• patients with cholestasis;
• conducting drug therapy with wolfarin, cyclosporine or other drugs that inhibit blood clotting;
• expecting a child;
• breastfeeding a newborn.
• under 18 years of age.

In the presence of oxalosis, pyelonephritis or other diseases of the kidneys and urinary system, Orlistat-Akrikhin should be used carefully and only under the constant supervision of a specialist.

Side effects

People losing weight with the help of the drug Orlistat-Akrikhin, according to their reviews, noticed the appearance of some side effects in the first 3 months of taking it.

Side effects:

• stomach cramps;
• flatulence;
• inflammation of the pancreas;
• transformation of feces into a liquid state, followed by involuntary bowel movements;
• increased activity of liver transaminases;
• an increase in the amount of alkaline phosphates in the blood;
• development of urinary tract infection;
• frequent migraines;
• increased anxiety and irritability;
• bronchospasms;
• hives;
• the occurrence of various allergic rashes and skin itching.

In particularly difficult cases, anaphylactic shock may occur.

Normally, unpleasant symptoms stop after treatment is completed. According to laboratory studies, increased unpleasant effects are caused by the combined use of Orlistat-Akrikhin with alcoholic beverages and fatty foods.

To reduce the severity of defects (the most unpleasant of which is involuntary bowel movement), when taking the drug, you should completely avoid eating fatty, fried foods and alcoholic beverages, including only low-calorie foods in your daily diet.

Taking the drug does not affect the ability to drive vehicles and does not slow down the speed of psychomotor reactions.

Negative aspects of the product

Much has been written about the benefits of Orlistat on sellers’ websites, but there are also disadvantages that manifest themselves in adverse reactions. The instructions for use say that the active substance causes flatulence, an increase in the number of daily bowel movements, loose stools, and even fecal incontinence. Oily discharge may come out of the rectum, and the stool may have a greasy consistency. Quite often, such adverse reactions frighten those losing weight, as can be seen from the reviews:

“This is a nightmare - after taking the capsules you always want to go to the toilet, your stomach sometimes swells, but what scares you the most is loose stools. This is how dehydration can happen.”

In the first days and weeks, the substance negatively affects the nervous system (as the manufacturer assures, not in all cases), so it may cause pain and dizziness, drowsiness or insomnia, and increased anxiety. In rare cases, intestinal steatorrhea and a lack of fat-soluble vitamins are observed.

Overdose

During laboratory studies, no cases of overdose were identified, but, according to the instructions, the drug intake should not be spontaneously adjusted, since increasing the dosage does not increase the therapeutic effectiveness of the tablets.

In case of overdose, it is recommended:

• urgently call an ambulance;
• drink up to 5-6 tbsp. water to induce vomiting to cleanse the stomach;
• take an absorbent that can stop the development of intoxication in the body.

Drug interactions

Orlistat-Akrikhin should not be combined with:

1. Levothyroxine sodium , due to the possibility of developing hemostasis with inadequate absorption of inorganic iodine;
2. Amiodarone . There is a sharp decrease in the drug in the blood.
3. Cyclosporine , due to the ineffectiveness of the lymphocyte-blocking properties of the drug.
4. Oral anticoagulants and warfarin , due to the possibility of increasing thrombin and INR in the blood.

Concomitant use of Orlistat-Akrikhin with oral contraceptives reduces the therapeutic activity of the latter, as a result of which additional (barrier) methods of contraception should be used during treatment.

The daily dose of the drug must be adjusted in case of simultaneous treatment:

• medications needed to lower blood sugar levels;
• drugs that normalize physical blood pressure indicators.

Since, due to the blocking effect of orlistat, the drug reduces the amount of fat-soluble vitamins and polysaturated acids entering the body during treatment, it is necessary to take daily supplements, including vitamins B, D, K, retinol and tocopherol.

Reviews

According to reviews from doctors and those losing weight, the use of Orlistat-Akrikhin helps to lose up to 5-7 kg during the first 4 weeks when combining the drug with a low-calorie diet and sports training.

Nutritionists note that drug treatment will be effective only if you refuse to consume fatty, high-calorie foods, a variety of sweets and carbonated drinks.

Experts advise taking the drug both to reduce excess weight and combat obesity, and to prevent a possible relapse of the pathology. The drug is effective for the treatment of people with diabetes and hypertension.

Taking the drug does not give the necessary results when:

• obesity caused by a sedentary lifestyle;
• weight gain due to hormonal imbalance;
• hypothyroidism.

While taking the drug, nutritionists advise eating as many different low-starch vegetables and fruits as possible, as well as adhering to a drinking regimen that includes consuming at least 2 liters of water per day.

Patients taking the drug speak well of the effectiveness of the drug, but note the appearance of unpleasant side effects that accompany the use, the greatest discomfort of which is constant diarrhea and uncontrolled bowel movements. This side effect most often occurs when Orlistat-Akrikhin is taken with fatty foods.

In what cases should you not take the drug?

Based on the annotation that comes with the drug, Orlistat has the following contraindications:

• allergic reaction to the main or auxiliary substances;
• hyperoxaluria and chronic malabsorption;
• nephrolithiasis and cholestasis;
• period of childbearing and lactation;
• age category up to 12 years.

According to official information, it is unknown how orlistat affects the child’s body and fetus. No studies have been conducted on the level of penetration of the substance into breast milk. But there are other reasons why the product should not be used while carrying a child. Reviews on the forums say this:

“I used these capsules before and successfully lost weight, but when I became pregnant and gained excessive weight, I decided to consult a gynecologist. So she said that the drug causes severe weight loss, and during this period it is prohibited, so she recommended an apple diet.”

Analogs

Analogues of the drug are the drugs described below.

Orsoten

A drug based on orlistat and microcrystalline cellulose that stops the absorption of dietary fats into the intestines by blocking active digestive lipases.

Regular use of the drug helps not only to reduce body volume, but also:

• remove accumulated toxic substances from the body;
• reduce the amount of cholesterol contained in the blood.

The drug is taken 3 times a day along with meals. The cost of the drug is from 800 to 1050 rubles.

Xenical

A weight loss drug containing orlistat, povidone and Primogel. The basis of the medicinal effect is the ability of the white crystalline powder to block the activity of digestive enzymes of the gastrointestinal tract (lipases) to break down fats supplied with food.

Undigested fats are removed from the intestines along with toxic substances under the influence of povidone-iodine.

Due to the effect, the body is cleansed, followed by severe weight loss. The effect of taking the drug occurs within 2 days after starting treatment.

The dosage of the drug is determined by the doctor individually, but normally it is allowed to take 3 capsules per day before or during meals. The cost of the drug is about 450 rubles.

Allie

Containing about 160 mg of orlistat, the drug prevents the absorption of dietary fats into cells, at the same time:

• cleansing the body of accumulated toxins;
• reducing the amount of cholesterol;
• normalizing the lipid composition of the blood.

Being highly selective, the drug does not affect the breakdown of protein and carbohydrate foods, slightly reducing the amount of vitamins and minerals entering the body. Taken simultaneously with meals, one capsule of trida per day.

The cost of the drug is from 750 to 870 rubles.

Reduxin

A drug used for weight loss based on sibutramine and monocrystalline cellulose, which helps fill the stomach and block the feeling of hunger, causing a false effect of satiety in a person.

In addition to weight loss, taking Reduxin is accompanied by:

• removing accumulated toxins, allergens, xenobiotics from the body;
• reducing the amount of cholesterol, triglycerides and uric acid in the blood.

The dosage of the drug is determined individually, depending on the amount of excess body weight.
The drug is taken once a day (preferably in the morning), along with meals. The cost of the drug is from 5800 to 6000 rubles.

Goldline

A drug based on sibutramine that helps regulate the feeling of hunger by causing the stomach to fill with microcrystalline cellulose, swollen under the influence of water.
Taking the drug:

• reduces the body's need for food;
• causes a false feeling of satiety;
• increases the body's thermal production;
• affects brown adipose tissue;
• reduces the concentration of cholesterol and uric acid in the blood.

The drug is indicated for the treatment of obesity in persons with a BMI of 30 kg/m2. m or more, as well as those suffering from type 2 insulin-dependent diabetes mellitus. It is recommended to use the drug once a day, before or during meals. The cost of the medicine ranges from 2200 to 5800 rubles.

Figurin

A combined weight loss product based on fruit extracts (guar gum, ginger, bhasma loja) with a mild laxative effect.

Promotes:

• weight loss;
• improving fat metabolism;
• complete digestion of food;
• reducing the amount of triglycerides and cholesterol in the blood;
• improvement of general well-being.

Indicated for obesity complicated by diabetes and hormonal imbalances. The drug is taken once a day. If the BMI exceeds 30, the daily dosage is increased to 2 times a day. The cost of the drug is 680 rubles.

Apetinol

An effective remedy for reducing appetite and subsequent weight loss.
Helps :

• prevent the feeling of hunger;
• reduce body weight;
• avoid late-night snacks;
• cause a faster feeling of fullness and, as a result, reduce the amount of food eaten;
• acceleration of lipid metabolism;
• removing toxic substances and excess cholesterol from the body.

Indicated to combat obesity and prevent overeating in people prone to night snacking and “eating” in stressful situations.

The recommended dosage of Apetinol is 2 capsules per day, taken 15-20 minutes in advance. before lunch or dinner. The price of the drug is about 150 rubles.

Orlistat-Akrikhin is a drug that helps effectively fight obesity by blocking the absorption of fats entering the body with food.

The use of the drug during a diet, according to reviews from patients losing weight, helps increase weight loss and helps to more quickly cleanse the body of accumulated toxins and toxic substances.

Orlistat: reviews, impressions

• I’ve always had problems with being overweight, and after giving birth I completely lost it. I tried many “starvation” diets, but nothing helped - the weight did not go away. I turned to a doctor for help, who advised me to try Orlistat. In 10 months of taking it, I lost almost 16 kg. Now I’m not losing weight so quickly, but I’m not going to stop. I have removed all high-calorie foods from my diet, and I give myself small daily exercise in the form of aerobic gymnastics. I take the drug three times a day. As for the side effects, at first there was slight discomfort in the stomach, which disappeared after about a month. I feel great and very satisfied. Marina.
• It seems to me that Orlistat is ineffective, despite the reviews. I’m finishing the second pack, but I see virtually no results. I seem to eat right, without sweets and fatty foods, but my weight stubbornly stays at 115 kg. Moreover, the side effects were tormenting (flatulence, several pieces of a tooth broke off!). I want to cry from all this, and even money is wasted. I’ll probably end the experiment; not everyone can be skinny. Vita.

• My doctor and I spent a long time selecting a drug for me to lose weight seriously and for a long time. We settled on Orlistat as the most acceptable option. The doctor developed a suitable diet for me, since I lead a fairly active lifestyle and do not always have time to “eat properly.” I have been taking Orlistat for six months, so my reviews are only positive. I really lost 10 kg and it’s inspiring. I don’t observe any side effects, but I even lost the habit of eating fat during this time. Elena.
• I really want to lose weight, but I'm afraid to take different pills. There are such horrors written in the instructions that it discourages anyone from even trying. I’ve been reading different reviews about Orlistat and really want to know the opinion of those who took the entire course: “Tell me, what happens to the weight then?” It is no secret that many drugs have the property that after the end of the dose, weight begins to gain at double the speed. Angelina.
• I have experienced the effects of Orlistat myself and I can say that it does not cause addiction. I took it for a whole year, following a diet. At the same time, I managed to lose significant weight without any problems. Now I’ve taken a break - I want to make sure that I don’t start to gain weight again. So far the weight has frozen, but I still continue to stick to the diet and move more. Hope.
• All these pills are for lazy people who cannot cope with the desire to treat themselves to pickles, but at the same time want to stay slim. Advertising will promise you mountains of gold if only you buy this drug. And then how it will turn out: someone will lose weight, and someone else will add to their soreness. Keep your mouth shut and go to the gym - this is the best recipe. Tamil.
• I heard stories from friends suffering from obesity (obesity) about the miracle drug Orlistat. Reviews from doctors about the drug were also encouraging. I carefully studied the instructions and was wary at first - they promised painfully unsightly side effects. But then I consulted with a nutritionist, who explained that all people are different, and there are scary side effects even in the instructions for aspirin. I took a risk and I don’t regret it at all. I’ve been taking it for four months, there are almost no side effects (it makes me weak, but in moderation) But the most important thing is that I’m losing weight! I think that by summer I will get into shape. I recommend everyone to try it. Rimma.

It should be noted that this drug should not be taken by those who suffer from chronic diseases such as diabetes, arterial hypertension, etc. Do not rush to self-diagnose obesity and prescribe Orlistat. Reviews about the drug vary, so be sure to consult with an experienced doctor . Don't forget that health is most important!

Author - Natalia Viktorovna, portal about weight loss WE LOSE WEIGHT without problems!