Lipoic acid for weight loss: properties, dosage, contraindications

There are several types of known acids that are indispensable for the human body, which are widely used by both cosmetologists and doctors. Ascorbic, nicotine, folic - these names are always heard, and we all know them well. But there are also drugs that are not so well known, and their invaluable impact on health is difficult to assess.

Lipoic acid is very popular for regulating metabolic processes in the body, and its prevalence is easy to explain. This drug is beneficial for lipid and carbohydrate metabolism, and also helps control cholesterol levels.

Therefore, its use in the treatment of diabetes, liver cirrhosis, excess weight, atherosclerosis, and it is also widely used by people who are professionally involved in sports, since it is one of the safest supplements.

Dosage

Like other vitamin-like substances, lipoic acid has its own consumption standards.
They will be different depending on age. Children under 15 years of age are recommended to take 12-25 mg per day, for adults - about 25-50 mg. During periods of intense physical or emotional stress, it is worth increasing your lipoic acid intake to 75 mg. If lipoic acid is part of a complex treatment program for any disease, then its dosage can be significantly increased. Please note that while taking lipoic acid you must avoid drinking alcohol.

Alpha lipoic acid has wonderful properties that will be useful for anyone who is trying to reduce body fat and reduce their weight. It is involved in the process of fat burning and promotes more active breakdown of fat cells during physical activity. In addition, when entering the body, lipoic acid enhances protein metabolism, due to which a person receives the necessary amount of energy. However, you must follow a strict diet.

To lose weight, lipoic acid should be consumed in the morning before the first meal, after training or at dinner. It is good to combine a portion of the supplement with carbohydrate foods.

To achieve maximum effect, you should strictly monitor your basic diet. It should be balanced and fully meet your daily needs for proteins, fats and carbohydrates. Avoid increasing feelings of hunger.

Alpha lipoic acid enhances the effect of vitamins E and C, which helps improve immunity and skin condition. In terms of the spectrum of biochemical effects on the body, it is similar to B vitamins.

Lipoic acid is involved in fat metabolism, stimulates cholesterol metabolism, and enhances the effect of L-carnitine. A vitamin-like substance promotes weight loss by dulling hunger, increasing energy production, improving glucose absorption, and increasing tissue sensitivity to insulin. It is involved in the release of energy from glucose, which allows the body to more efficiently waste useful components obtained from food, without storing them for a rainy day.

In addition, the substance enhances the effect of other antioxidants – ascorbic acid and tocopherol.

Do not take this medicine without consulting your doctor. Uncontrolled consumption of thioctic acid supplements may lead to hypoglycemia or reduce the effectiveness of hormonal treatment.

Athletes take dietary supplements (BAA) 3 times a day and always after training. As prescribed by the doctor, the drug is drunk at a time, in the morning.

Over time, thioctic acid practically ceases to be produced by the body. The older a person gets, the more deficient this substance (vitamin N) becomes. Therefore, after 35 years, it is recommended for every person to use it, especially for those who want to lose weight. If you do this, taking into account the required dosage, it will not accumulate in cells in excess of the required amount. It should be calculated by a qualified doctor, and the following must be taken into account:

your lifestyle;
target;
age;
health status;
weight;
powder digestibility;
portability.

Attention! Not only a person with poor health needs consultation from a specialist, but also someone who has no problems with it. This is due to the fact that thioctic acid has increased activity, which may cause certain side effects.

A healthy man who wants to lose weight needs at least 50 mg and no more than 200 mg. It turns out that a person should take from 1 to 4 tablets per day, without chewing them and washing them down with water. This dose should be drunk several times, and the best time for this is half an hour before breakfast, after sports training (immediately, no later than 15 minutes) or at dinner, at the time of the last meal.

For women with extra pounds, the instructions for using lipoic acid recommend drinking a smaller dose - 50 mg per day (2 tablets) will be enough for them. They need to be taken in exactly the same way as for men, only in this case you can divide one serving into two. To enhance the weight loss effect while taking the drug, it is recommended to exclude foods rich in quickly digestible carbohydrates from your menu.

These include:

buckwheat;
dates;
bananas;
rice, both white and brown;
honey of any origin;
bread made from all types of flour;
legumes;
semolina;
pasta;
potato;
sweets;
flour products, except those made from whole grain flour.

If at least one of the side effects occurs, we can talk about an overdose of the drug. Also, muscle pain, dizziness and intestinal upset can indicate this. In this case, you must immediately stop taking it and consult a doctor.

I turned to a nutritionist, realizing that I was already tired of fighting excess weight using classical methods. Exhaustive diets, constant attempts to force myself to regularly go to the gym and pool, intentions to run every morning - all this crashed against the harsh rocks of stressful work. I would break down, stop working out, miss out on runs, and ultimately start to hate myself.

And the age of “just about forty” already hinted that it was time to come to terms and stop tormenting yourself and your loved ones. The family steadfastly endured the mood changes and breakdowns that followed the emergence of a “magic” hobby in the fight against extra pounds, for which we thank them. My husband insisted that if I really wanted to lose weight, I should go to a nutritionist.

https://www.youtube.com/watch?v=2R3oljxtKCM

He immediately, without looking at the card, after listening to me, guessed my lifestyle, age, and marital status (also the number of children). He explained quite clearly that by the age of forty, a woman’s body undergoes noticeable changes, some things stop being produced, and some things start to turn out the other way around. Prescribed 50 mg of liepic acid per day.

I strongly recommended gradually eliminating (or reducing to a minimum) the consumption of foods rich in fast carbohydrates. And now about the sweetest part. The course was designed for 3 weeks. And in these three weeks I lost 4.2 kilograms! Going from 63 kg to 58.8 kg is a huge success for me! And, more importantly, the barrier has been overcome psychologically, I know that I can be even slimmer! And I definitely will! Anastasia, 39 years old.

I have the same story as Nastenka from the previous review. Only I’m 34, and the rest is exactly the same! Also stress, breakdowns, children... The result is worse - from 66 kg to 64 kg, but only two weeks have passed, so I’m really, really looking forward to finishing the course!! Natalie, 34 years old.

Dosage recommendations vary depending on the intended use. The following are general guidelines that are within the safe range:

50–100 mg/day for antioxidant purposes in healthy adults.
600–800 mg/day for patients with diabetes (divided into two doses).
600–1800 mg/day for patients with diabetic neuropathy (such high doses should only be taken under medical supervision).
600-1200 mg/day for weight loss.

Some of the best food sources of alpha lipoic acid are: broccoli, spinach, red meat, organ meats (beef or chicken liver, hearts, kidneys), Brussels sprouts, tomatoes, peas, brewer's yeast, beets, carrots.

Lipoic acid was used to treat liver diseases that could be associated with excessive alcohol consumption. A little later, the product began to be used by athletes and bodybuilders to improve their physical fitness. Now LC is used to speed up the process of losing excess weight. When taking LA, metabolism accelerates. It is the speed of metabolic processes that influences the effectiveness of weight loss.

Alpha-lipolyic acid helps normalize the functioning of almost all organs, which helps to effectively lose excess weight. For example:

Reduces sugar levels. This is justified by the fact that glucose absorption is normalized, carbohydrate balance becomes close to ideal, and appetite decreases. By reducing the portion size, a person will not face the feeling of constant hunger.
Prevents the formation of fatty deposits. This substance is not a fat-burning agent, but it is vitamin N that reduces the amount of fat deposits. Previously formed fat can only be removed through physical exercise.
Accelerates the absorption of glucose. It is this factor that influences human activity. With a low-calorie diet and taking LA, you can play sports without harm to your health.

It is these properties of the acid that allow you to lose weight without discomfort, hunger and irritability, increasing the effect of low-calorie diets.

How to take lipoic acid for weight loss? In what doses should the drug be taken for the weight loss process to be effective? Thioctic acid, according to its chemical composition, can give a different reaction under the influence of any compounds. You should not prescribe your own dosage. With this question, it is better to contact an appropriate specialist who will help you choose an individual dose specifically for your body.

LA is used as part of complex preparations. or in the form of dietary supplements. Manufacturers produce the drug in different dosages, but it is up to the doctor to find your individual dosage.

The most common types of thioctic acid dosages are as follows:

If the patient does not have specific indications, then he can consume up to 50 mg of the substance per day;
An increased dose (75 mg) is prescribed exclusively in the case of complex treatment of kidney, liver or heart diseases;
LA for weight loss is approved for diabetics at the following dosage: at least 400 mg per day;
The dosage of thioctic acid for people who do not have health problems is 100 mg per day;
The dosage of the drug can be increased to 500 mg per day if a person is actively involved in sports.

Natural Sources of Vitamin N

Vitamin N is partially produced in the body and accumulates in the liver and kidneys. If a woman leads a healthy lifestyle and eats right, then this amount of lipoic acid is quite enough.

The vitamin is found in both animal and plant products.

Most of it is in:

beef and pork;
offal , including chicken;
soy;
linseed oil;
nuts;
cereals;
vegetables and mushrooms (garlic, celery, champignons, potatoes);
black currant;
green onions and lettuce leaves;
Brussels sprouts and white cabbage.

To ensure complete absorption of lipoic acid, you need to separate the consumption of the above foods and dairy products. The break between doses should be at least 2 hours.

Advantages and disadvantages

Before you start using Alpha Lipolyic Acid, you should carefully familiarize yourself with all the advantages and disadvantages of this product.

ALA is taken for weight loss because it:

inexpensive;
normalizes cholesterol;
improves the functioning of the nervous system;
protects the liver from negative effects;
increases energy, improves mood;
provides a protective function against sunlight;
reduces the number of stretch marks on the skin;
helps people with diabetes reduce the risks associated with eye disease;
normalizes the functioning of the thyroid gland;
makes the immune system stronger and more stable;
increases the number of bacteria beneficial to microflora;
metabolic processes will accelerate, metabolism improves. Losing weight with LC is more effective;
You can take the product without following a strict diet.

But you should pay attention to the following features:

Side effects may occur. To prevent lipoic acid from causing a negative reaction, the dosage must be observed;
To achieve greater results, you need to take several courses. This is necessary because the medicine is not recommended to be used for too long a time. If you intend to get rid of extra pounds, then several courses are necessary;
complete incompatibility with alcohol in any quantity;
Since this product is a dietary supplement, its cost is significantly higher than a regular drug.

It should be understood that in the absence of physical activity, the medicine will not have a positive effect.

Reviews

Reviews about lipoic acid and weight loss:

Alexandrova Anastasia

Nutrition and healthy lifestyle specialist and author of myfitnesblog.com. For many years, she has successfully helped women and men lose weight and maintain a beautiful figure.

How it works

The mechanism of action of lipoic acid is based on the fact that it:

reduces hunger;
converts substances supplied with food into energy;
lowers blood glucose levels;
burns fat;
restores liver function under heavy loads on it under heavy weight conditions;
restores nerve endings.

Due to the effect of the drug on the body, metabolism is significantly improved, breakdown products and toxins are eliminated, and fat is removed. But the most important thing is that under the influence of lipoic acid, carbohydrates are transformed into useful energy, which is wasted during sports. This causes a person to lose weight, and this is an excellent preventive measure against extra pounds.

Lipoic acid accelerates the effect of acid working in three main directions.

Neutralizes free radicals. Radicals are waste products formed in the internal environment of the human body. As they accumulate, they can have a negative effect on healthy cells, causing premature aging processes. In addition, it is free radicals that can worsen a person’s condition, making him lethargic and tired.
Controls glucose levels. The better sugar is absorbed in the body, the less fat deposits a person develops.
Accelerates the metabolic process. The most important principle of any diet is to expend more energy than you consume. It is lipoic acid that will reduce the feeling of hunger, while increasing energy expenditure.

Taking this vitamin is also prescribed in case of acute deficiency. You can start a course of taking acid if:

alcohol abuse;
in the absence of red meat in the diet;
excess weight;
diseases of the gallbladder or liver.

A specialist will tell you how to take lipoic acid if you notice certain symptoms. You should not self-medicate so as not to aggravate the situation.

Compatibility with other drugs

Losing extra pounds using lipoic acid with B vitamin therapy increases the effects of both drugs. The effect of medications that lower blood sugar increases.

But any amount of alcohol will reduce the effect of the drug; drugs containing metal compounds (calcium, magnesium, iron) have the same properties. Using solutions of glucose, fructose and other sugars together with lipoic acid is fraught with side effects.

Contraindications

ALA lowers blood sugar levels, so diabetics should monitor their sugar levels closely.
Avoid taking alpha lipoic acid with monocarboxylic acids, benzoic acid. They may compete for absorption and reduce the activity of both compounds.
Raw egg whites may also reduce or counteract the beneficial properties of alpha lipoic acid.

Alpha lipoic acid supplements have not been studied in children or pregnant or lactating women.

Alpha lipoic acid is quickly absorbed by nerve, brain and heart cells. This allows you to use it not only as

, but also as a medicine in the treatment of many diseases. Among them:

diabetic neuropathy;
atherosclerosis;
diabetes;
liver diseases;
Alzheimer's disease;
multiple sclerosis;
oncological pathologies;
alcoholism;
glaucoma;
cataract;
various poisonings;
memory problems.

Lipoic amino acid should not be taken by children under 6 years of age, during pregnancy and breastfeeding, if there is sensitivity to certain components and in combination with taking blood thinning and

, magnesium, Cisplatin.

Lipoic acid should not be used by children under 6 years of age and people with hypersensitivity to the drug. It is necessary to take it with caution during pregnancy or lactation. In the latter case, it is better to consult a specialist.

Instructions for the use of lipoic acid, in order to avoid malfunction of the body, prohibit drinking it in the following cases:

age up to 6 years;
individual intolerance to the components of the drug;
gastritis, both with high and low acidity;
ulcer, both closed and open;
pregnancy (the drug should either be excluded altogether or taken with caution).

It is not recommended to take alpha lipoic acid in the following cases:

during pregnancy and lactation;
children under 16 years of age;
for allergic reactions and individual intolerance to the drug;
adults over 60 years of age;
with high blood pressure;
when taking certain medications.

What are the benefits of thioctic acid?

The benefits of lipoic acid are as follows:

Reduces oxidative stress in the body thanks to powerful antioxidant activity;
Improves some components of metabolic syndrome - a combination of risk factors that increase the risk of developing diabetes;
Reduces blood pressure;
Reduces insulin resistance;
Improves lipid profile;
Reduces body weight;
Improves insulin sensitivity;
Reduces the severity of diabetic polyneuropathy;
Prevents the appearance of cataracts;
Improves visual parameters in glaucoma;
Reduces brain damage after a stroke;
Reduces bone loss due to anti-inflammatory properties;
Removes heavy metals from the body;
Reduces the frequency and severity of migraine attacks;
Improves the structure and condition of the skin.

Dosage

Many resources may also indicate that you should consume up to 200 mg of alpha lipoic acid per day to achieve greater results. Doctors recommend starting any drug with small doses to avoid side effects and overdose.

The period of taking lipoids is always strictly limited to 3 weeks. The break between courses should be 1-2 months. After which the course can be repeated.

special instructions

If the drug is used intramuscularly, it is best to administer it in the morning or evening.

When taking ALA in the form of dietary supplements or as part of medications, problems with the gastrointestinal tract may occur. To prevent stomach problems, it is recommended to take the medicine after meals.

Vitamin N interferes with the absorption of calcium, for this reason it is better to eat dairy products 4-5 hours after taking ALA.

Lipoid acid is consumed by athletes, as a rule, 30 minutes after the start of active exercise.

Lipoate and alcohol should absolutely not be combined. Alcohol does not allow all the properties of the vitamin to manifest themselves. Moreover, it often causes dizziness and vomiting.

After 2 or 3 weeks after using LC, the urine may have a peculiar odor. This is an absolutely normal reaction, you should not be afraid of such changes.

If you are taking other serious medications, consult your doctor. This will help you find out exactly the compatibility of the two products.

Repetition helps. Does Alpha Lipoic Acid Lose Weight Without Exercise? Alas, taking this substance without additional activity will not give any results.

Side effects

If you follow all dosage standards, then there will be no side effects at all. Any ailment that is associated with taking ALA can only arise from an overdose or from too long a course of use. Symptoms of overdose include:

stomach discomfort;
skin rashes, itching, eczema;
anaphylactic shock;
headaches, high blood pressure;
nausea, diarrhea;
convulsions, respiratory dysfunction.

If these symptoms appear, you should stop taking the drug.

Do not assume that a larger dose will immediately achieve a better effect. Overdose is extremely dangerous. In critical cases, the following types of assistance should be provided:

gastric lavage or artificially induced vomiting;
consumption of activated carbon;
symptomatic therapy.

Contraindications

Contraindicated in the presence of the following factors:

any allergic reactions caused by the drug;
pregnancy, lactation;
age not exceeding 16 years;
gastritis or other stomach problems.

Ignoring these contraindications can have a detrimental effect on a person’s health and well-being.

It is strictly prohibited to use ALA simultaneously with insulin. The explanation for this is simple: both drugs can sharply reduce the concentration of sugar in the blood. In addition, it is not recommended to use vitamin N while taking calcium, magnesium or iron.

Storage conditions

The drug in capsule form should be stored in its original packaging, avoiding moisture. The injection is very sensitive to light, for this reason the drug should be stored in dark places. After the expiration date, the drug is disposed of; its use is strictly prohibited so as not to cause poisoning.

Indications for use

The list of indications for taking lipoic acid is constantly expanding as scientists conduct new research. Today the drug is prescribed for the following conditions:

Diabetic nephropathy.
Damage to nerves and nerve cells.

Advice: You should not drink lipoic acid if you need to take other medications, even dietary supplements. The features of its interaction with other substances have not yet been fully studied. Such experiments are possible only under medical supervision.

Glaucoma.
Poisoning with toxins and poisonous mushrooms.
Liver cirrhosis and hepatitis.
Diabetes.
Atherosclerosis.
Alcoholism.

The effectiveness of treatment with lipoic acid has also been established for complications of HIV and radioactive radiation. Scientists believe that the substance slows down the aging process.

What foods contain alpha lipoic acid?

Lipolyveic acid is found in the following types of foods:

veal;
beef without fat;
cabbage;
broccoli or spinach with celery;
boiled rice;
yeast (brewer's);
pepper (not bitter).

It is the intake of these products that will help maintain the level of vitamin composition in the body, which will maintain the metabolic rate without slowing down.

The main sources of lipoic acid are animal products - heart, kidneys and liver. It is also found in large quantities in various legumes: lentils, peas, beans. Small amounts of acid can be obtained from bananas, mushrooms, yeast, rice, spinach, cabbage and dairy products.

The human body is capable of producing lipoic acid on its own. But even taking into account the amount that can be obtained from food, the level of its content will be insufficient for the healthy functioning of the body. Therefore, doctors advise paying attention to additional intake of alpha lipoic acid in the form of a supplement. It is available in several forms: in the form of capsules, powder and ampoules for intravenous injection.

Application for facial skin

The antioxidant and anti-inflammatory properties of alpha lipoic acid work wonders when it comes to reducing the visible signs of aging. Lipoic acid is a beneficial and amazing antioxidant and is 400 times stronger than vitamins C and E. When used topically, alpha lipoic acid benefits the skin of the face - reducing puffiness and dark circles under the eyes, facial swelling and redness. Over time, the skin appears smoother due to increased production of nitric oxide, pores become smaller, and wrinkles become less noticeable.

How to use bisacodyl - dosage, contraindications Fluoxetine tablets - instructions

Expert opinion

This fatty acid is a powerful lipophilic antioxidant that is naturally synthesized by the body and is found in every cell of the human body. But in some chronic diseases (such as diabetes), as well as with age, its synthesis decreases, and in various clinical conditions associated with oxidative stress, the body may require its additional administration from the outside.

ALA is found in red meat, liver, heart, kidneys, green vegetables, spinach, broccoli, tomatoes, peas, potatoes, beets, carrots, yeast and many other foods. In its pure form it is produced both as a medicine and as an ingredient in dietary supplements.

from alcoholic neuropathy and vibration disease to multiple sclerosis and impaired sense of smell. It is even used for weight loss. But... if the diet remains unbalanced (and also contains a large number of desserts), the effect of taking ALA will be temporary. We must also remember that it “works” to shed excess pounds only in combination with physical activity, and - most importantly - does not at all affect the causes of excess weight in a person.

That is, the weight lost with its support will inevitably return again. Therefore, it is not worth treating it as a cure for obesity. Some help for relatively quick weight loss for a while? Yes. A way to permanently (forever) get rid of extra pounds? Unfortunately no. In contrast to the normalization of eating habits and their further support by psychotherapeutic methods

Thus, lipoic (thioctic) acid can indeed in some way help accelerate the utilization of glucose and the breakdown of fats, but not on its own, but in the complex treatment of obesity while maintaining a balanced diet and maintaining a higher level of physical activity. Under normal conditions, it remains an effective antioxidant and detoxifying agent.

Instructions for use

In order for body modeling with lipoate to bring results, it is important to know exactly how to correctly calculate the dosage and duration of the course. Thioctacid is particularly chemically active and reacts with other compounds, so you should study the specifics of its use in advance.

Dosage

Since the substance enters the pharmaceutical market in the form of medicines and dietary supplements, manufacturers make their own recommendations regarding the dosage of lipoic acid for weight loss. Doctors have established special rules regarding how to use the drug, subject to the law “do no harm”:

in the absence of medical indications, the daily dose of ALA is up to 50 mg;
a dose of 75 mg can be used exclusively in the complex treatment of liver, heart and kidney diseases;
diabetics are usually prescribed at least 400 mg of vitamin N per day;
the maximum daily dose of thioctacid for healthy people is 100 mg;
with a significant increase in physical activity, the dose of thioctacid can be increased several times, with high-intensity cardio training - up to 500 mg.

If the issue of weight loss is being considered, the minimum dosage for women is 30-50 mg per day (10-15 mg three times a day), for men - 50-75 mg (20-25 mg three times a day). The dosage when administered by intramuscular injection should not exceed 50 mg. Some sources indicate that results can only be achieved by taking 100-200 mg of ALA per day. In any case, in order to prevent the development of a negative reaction of the body, you should start taking it with small doses.

Neurologist D. Perlmutter, who is the author of the “brain nutrition diet,” calls 600 mg of LA a mandatory daily dose for anyone who wants to eliminate the consequences of many years of abuse of fast carbohydrates. In fact, without a doctor’s prescription and the necessary physical activity, such an amount of thioctacid can result in a sharp deterioration in well-being.

The duration of one course of weight loss on lipoate is limited to 2-3 weeks, although to achieve a high-quality result it is possible to increase the duration to 1 month. Further use of the substance without interruption is impossible, as there is a real risk to health. The optimal interval between courses is 1 month, but it is better to maintain two.

special instructions

The best time to take (intramuscularly) LA is morning and evening.
To prevent the development of discomfort in the gastrointestinal tract, the use of ALA in the form of medicines or dietary supplements should be done after meals.
Dairy products should be consumed at least 4 hours after taking vitamin N as it reduces calcium absorption.
Athletes should consume vitamin N half an hour after finishing training.
It is strictly forbidden to combine lipoate and alcohol. The latter blocks the beneficial properties of vitamin N. In addition, while losing weight with lipoic acid, large amounts of alcohol can lead to the development of nausea and dizziness.
After several weeks of active use of ALA in the form of oral preparations or a solution for intramuscular injection, the urine may acquire a specific odor. This moment should not alarm or frighten, as it is the norm.
It is better to stop taking serious medications while using ALA, but first you should talk to your doctor.
Losing weight with alpha lipoic acid should not be “passive.” To improve your results, you need to exercise and eat right. There is an explanation for this. With intense training, microtraumas occur in the muscles, and when the diet changes, chemical changes are triggered in the body. Under the pressure of these circumstances, oxidative processes are activated in the body, causing an acceleration of the formation of free radicals. Having neutralized them, LA is “restored” and again heads for its antioxidant effect. The result of an integrated approach to weight loss is noticeable after 1.5 weeks from the start of the course. In general, in 3 weeks you can become 4-7 kg lighter.

Side effects

As a rule, side effects when consuming lipoic acid are extremely rare. The exception is an overdose and an excessively long period of use. If the following symptoms occur, taking capsules, tablets and other forms of LA should be stopped immediately:

stomach ache;
anaphylactic shock;
skin rash;
hyperemia throughout the body;
headache;
metallic taste in the mouth;
diarrhea;
hypoglycemia;
hives;
skin itching;
increased blood pressure;
convulsions and double vision;
holding your breath;
eczema;
nausea and vomiting.

Since thioctacid affects the level of thyroid hormones, if used incorrectly, hypothyroidism is likely to develop. The condition is accompanied by the following symptoms: yellowing of the skin, decreased body temperature, decreased blood pressure, chills, anemia, drowsiness, and disruption of the menstrual cycle.

If vitamin N is used in the form of a solution for the preparation of injections, hemorrhage into the mucous membranes and skin is added to the side effects.

Some people who are losing weight think that increasing the daily dosage of the substance will lead to faster weight loss and bring more benefits to the body. This opinion is extremely wrong. Rather, on the contrary: an overdose is life-threatening, as it even leads to hypoglycemic coma and blood clotting disorders. The following methods are prescribed to help in critical conditions:

symptomatic therapy;
gastric lavage;
artificial induction of vomiting;
taking activated carbon.

It is important to know that all of these manipulations may be useless, since medicine does not know a specific antidote. That is why, before drinking LA or performing injections with solutions containing it, you need to carefully study the instructions.

Contraindications

Ignoring contraindications to the use of vitamin N can lead to negative consequences for the entire body, so they should be studied with particular seriousness:

allergic reactions;
pregnancy and lactation;
age up to 16 years (in some sources – up to 6 or 14);
gastritis;
exacerbation of peptic ulcer of the duodenum and stomach;
increased acidity of gastric juice.

Drug interactions

Due to the risk of excessively low blood sugar levels, lipoate should not be taken at the same time as insulin. Cisplatin reduces the effectiveness of vitamin N. Also, the ban on simultaneous use applies to vitamin complexes containing calcium, magnesium and iron.

Storage conditions

Thioctacid capsules and tablets should be stored in the original packaging and protected from contact with moisture. Ampoules for preparing the solution are highly photosensitivity, so it is important to avoid direct sunlight. After the expiration date established by the manufacturer, the use of LC in any of the forms presented on the pharmaceutical market is prohibited in order to avoid poisoning.

Where to buy alpha lipoic acid

You can buy alpha-lipoic acid from our partners, in the iHerb online store, using the links below:

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Functions of acid

Energy production - This acid finds its place at the end of a process called glycolysis, in which cells create energy from sugar and starch.

Preventing cell damage is an important role of antioxidant function and its ability to help prevent oxygen deprivation and cell damage.

Supports the absorption of vitamins and antioxidants - lipoic acid interacts with water-soluble (vitamin C) and fat-soluble (vitamin E) substances, and therefore helps prevent deficiency of both types of vitamins. Other antioxidants such as coenzyme Q, glutathione, and NADH (a form of niacin) are also dependent on the presence of lipoic acid.

Composition and release form

Thioctic acid is sold in two forms, one of them is 0.025 g tablets. They are coated with a thin transparent coating and packaged in 50 pieces. in cardboard packages or glass containers. They come with instructions for use. The drug is available in ampoules as a 0.5% solution of 2 ml in one. The former need to be taken orally, the latter are intended for intravenous and intramuscular injections. Pills are mainly used for weight loss.

https://www.youtube.com/watch?v=84b8wMi-mlA{amp}amp;list=PL8MT9ubBJsytQ18faOuCtza2hsN7Drs1I

The composition of the drug includes:

talc;
sucrose;
potato starch);
glucose;
calcium stearate;
stearic acid.

Drugs

The drugs containing LA on the market today can be divided into three groups:

Medicines

Medications with LA are the most primitive group that can, but is not advisable to be used for weight loss due to the high risk of developing negative reactions if used incorrectly. The drugs are often available as tablets (t) and solutions. Particularly recognizable:

Berlition. A drug for regulating metabolic processes. Prescribed for the treatment of diabetic neuropathy, hepatitis, chronic intoxication. One of the most popular drugs containing LA. Cost - from 750 rubles for 30 tons, and 550 for 5 ampoules.
Lipothioxone. A medication with an antioxidant effect that regulates lipid and carbohydrate metabolism. Used for diabetic polyneuropathy. Price – from 440 rubles for 5 ampoules.
Thiolipon. The product is an endogenous antioxidant that binds free radicals. Used in the treatment of diabetic polyneuropathy. The cost of 30 tons is approximately 850 rubles, and 10 ampoules are 450.
Thioctacid. A lipid-lowering drug that has a positive effect on the metabolic process. Used in the treatment of hepatitis, cirrhosis, diabetes. Price – 1800 rubles for 30 tons and 1630 – for 5 ampoules.
Espa-Lipon. A means for regulating metabolic processes, indicated for effectively combating the manifestations of diabetes mellitus. Cost – 760 rubles for 5 ampoules.
Octolipen. The metabolite, which normalizes metabolic processes, actively fights existing fat deposits. Cost 30 tons - 340 rubles.

The average content of active substance (AL) in the presented products is 300 mg per dose.

It is quite possible that the effect of taking these medications in relation to weight loss will not be noticeable immediately due to the lack of additional substances with fat-burning and metabolic effects, but you will be able to get rid of several kilograms if you exercise and eat properly.

dietary supplements

It is much more advisable to use vitamin N for weight loss in the form of dietary supplements, additionally enriched with various components. Their range on the market is quite wide. Each manufacturer clearly states how and how much to take the drug, which is very convenient.

In isolated form, that is, without additions, ALA is represented by the following drugs:

"Active Lipoic Acid" from Country Life

The kosher food supplement is a heat-stable R-lipoic acid (30 mg) combined with alpha lipoic acid (270 mg), which guarantees greater effectiveness when taken and the fastest achievement of results in the form of body rejuvenation and weight loss. R-lipoic is the “right-handed isomer” of lipoate, with a slightly different molecular composition. Doctors are confident that the human body absorbs this type of ALA more efficiently, since the substance has a greater potential for the inherent properties of LA and significantly increases the sensitivity of cells to insulin. The price of the drug is 1491 rubles for 60 tablets.

"Alpha-Lipoic Acid" from Doctor's BEST

The American company supplies the market with dietary supplements in three samples - with ALA content of 150, 300 and 600 mg per serving. Some of the products can be consumed by vegetarians. Cost – 688 rub.

Alpha Lipoic Acid by Solgar

The American company Solgar produces a kosher dietary supplement without gluten and wheat, suitable for vegetarians. Each serving contains 120 mg of active substance. There are 60 capsules in a package. Price – 685 rub.

"Alpha Lipoic Acid" from Evalar

The product of the Turboslim line, marked “Anti-age”, in the production of which raw materials from leading German manufacturers are used, is an easily digestible ALA for antioxidant protection and detoxification of the body. Additionally, it provides the opportunity to protect liver cells, control weight and reduce blood sugar levels. Allowed for children over 14 years old. The price of lipoic acid for weight loss from Evalar is 307 rubles for 30 soft gelatin capsules. Each contains 100 mg of the active ingredient, which does not exceed the permissible level.

"Lipoic acid" from Kvadrat-S

A dietary supplement from a Russian manufacturer is supplied to the market in the form of film-coated tablets. Recommended as an additional source of LC. In addition to influencing appetite and reducing weight, it strengthens the immune system and affects lipid metabolism. Each serving contains 30 mg LA. The average cost of 30 tablets is 60 rubles.

"ALK" from DHC

DHC is considered a leader among Japanese dietary supplement manufacturers. Her product with LA is considered indispensable for everyone who wants to achieve an ideal figure, healthy skin and well-being. It is marketed in capsule form, each containing 210 mg of ALA. For a package of 40 capsules they ask from 1000 rubles.

The list can be continued for a long time, since almost every sports nutrition company strives to release its own ALA product. These are considered the most effective.

A more modest range of thioctic acid dietary supplements with additives that trigger an accelerated weight loss process and bring maximum benefit to the body.

The American manufacturer Jarrow Formulas offers a special type of dietary supplement - “ALA with Biotin” (Alpha Lipoic Sustain). Extract is a dual-layer, sustained-release format for less GI irritation. Biotin is included for optimal action of the main component. Each tablet contains 300 mg of thioctacid. You can purchase a pack of 60 tablets for 1,158 rubles.

Another complex with two components essential for weight loss is “Acetyl-L-Carnitine and ALA” (Acetyll-Carnitin Alpha-Lipoic Acid) from Source Naturals. The dietary supplement from the American pharmaceutical company is intended not only for fat burning, but also for vitality at the cellular level. The content of two nutrients allows you to maintain metabolic functions at the proper level. Acetylcarnitine is a relatively new form of levocarnitine to which an acetyl group has been added. According to the manufacturer, acetyl-L-carnitine has greater bioavailability and is more effective. One tablet contains 500 mg of acetyl-levocranitine and 150 mg of ALA. There is no strictly defined dosage - you can take from 1 to 4 tablets per day. You need to focus on your own goals and well-being. The price of the dietary supplement is 1,555 rubles per pack of 60 tablets.

A good choice among the “mixes” is considered to be the product from the Turboslim line from the Russian company Evalar “Alpha-Lipoic Acid and L-Carnitine” . A combination of two substances that accelerates metabolic processes is often used in sports and for weight loss. L-carnitine itself is produced by the body in the same way as ALA, that is, both components are natural. Thanks to levocarnitine, cholesterol and triglycerides are reduced, fat deposits are broken down and the body is provided with energy. The substance increases overall tone, increasing mental and physical activity, and also accelerates muscle recovery after training. The effectiveness of the drug "Alpha Lipoic Acid and L-Carnitine" in the matter of weight loss is due to the active burning of fats and the release of energy. Additionally, the dietary supplement contains a complex of B vitamins, which enhances the energy-producing properties of the main components and helps improve all types of metabolism.

ALA enhances the fat-burning effect of the natural anabolic L-carnitine.

The dietary supplement is available in tablet form. Each contains at least 30 mg of alpha lipoic acid and at least 300 mg of levocarnitine. The manufacturer recommends taking 2 tablets per day, thereby forming the optimal daily dose of active ingredients for guaranteed weight loss. The cost of Russian-made dietary supplements on the official Evalar website is 289 rubles. per pack of 20 tablets.

If you don’t want to swallow pills, you can choose a dietary supplement from the same ]Turboslim Alpha[/anchor]. This is a fat-burning drink to speed up metabolism, containing l-carnitine. A dietary supplement with a high concentration of natural fat burner is perfect for those who want to shape their figure. Helps speed up metabolic processes, increases training efficiency and restores strength. A special feature is ease of use: since the dietary supplement is not a concentrate, it does not need to be diluted with water. The package contains 6 bottles of 50 ml each. Cost – about 450 rubles.

Important! Dietary supplements with ALA should be taken strictly in accordance with the prescribed course duration. Otherwise, you can accustom the body to a constant supply of a substance that stimulates metabolism and cause a “withdrawal syndrome,” which results in the body refusing to independently produce thioctacid.

Vitamins

The ALA content in vitamin complexes is not as high as in dietary supplements and medications, which is why they are used for preventive purposes. In the case of weight loss, use is possible to maintain the achieved result.

The following complexes are especially popular on the market:

“Complivit” (2 mg) and “Complivit Diabet” (25 mg) from the Russian company Pharmstandard. Cost – from 140 rub. for 60 tablets.
Vitamin and mineral complex AlfaVit Effect. Designed for people actively involved in sports and fitness. It contains lipoic and succinic acid, as well as natural energy drinks: taurine, carnitine and plant extracts with a tonic effect. Daily dose – 3 tablets of different colors. A package of 60 tablets will cost approximately 380 rubles. The company also produces the “During the Cold Season” complex, which also contains lipoic and succinic acid. 60 tablets will cost 300 rubles.
"Selmevit Intensive", Slovenia. In addition to ALA (25 mg per dose), it contains a loading dose of B vitamins. The complex is designed specifically for people leading an active lifestyle. Price – 380 rub. for 60 tablets.

Despite the fact that lipoate is one of the few means for weight loss without harm to health, you should consult your doctor before starting the course. If your goal is to lose weight, it is better to use dietary supplements rather than medicine.

Special instructions for use

You should use lipoic acid for weight loss for at least 20 days, then, if the results obtained are not satisfactory, you need to take a break for a week or two and start all over again. It is important to consider that the dose should exceed the usual one specified in the instructions for the drug. During this time, with the right approach, you will be able to lose 5 to 10% of your total initial body weight.

It is also necessary to remember that the shell of the tablets (if they are used and not the solution) is made from lactose. For this reason, they should be used very carefully by people with intolerance (allergy). Another important point is the risk of decreased sensitivity due to the renewal processes occurring in nerve cells. This is mainly characteristic of people suffering from polyneuropathy.

Those who are losing weight with high blood sugar should also be vigilant. If its level is significantly exceeded, above 6, it is necessary to urgently reduce the dosage of glucose-lowering tablets or insulin. But before that, be sure to consult a doctor!

On a note! When planning to switch to lipoic acid, it is important to avoid eating iron-rich foods. The leaders in its content are beans, oatmeal, lentils, prunes, cocoa, dried pears, mushrooms and peas. In addition, losing weight will not bear the desired fruits if you do not stop drinking alcohol, even the most harmless one. It reduces the effectiveness of the tablets.

What results can be achieved?

By carefully studying the instructions for the drug, you can achieve certain absolutely short-term results by using lipoic acid:

Metabolism increases.
Fat burning is stimulated.
Stretch marks are reduced.
The youthful condition of the skin is maintained.
Due to the increased absorption of vitamins, immunity will improve.

Subject to the correct dosage, diet and physical activity, the first results will be noticeable after 1.5 weeks from the start of taking the drug. In a month of such therapy you can lose up to 7 kg of excess weight.

Side effects

Taking lipoic acid incorrectly can cause the following:

activation of the sense of appetite;
a sharp decrease in blood sugar levels to a critical state;
depression and lack of strength;
allergies;
difficulty breathing;
increased sweating;
stomach pain;
vomiting;
nausea.

When studying the effects of lipoic acid on the human body, no significant negative consequences were identified. Even when combined with other antioxidants: vitamins A or C, L-carnitine or green tea extract. However, if the recommended dosage is exceeded excessively, side effects may occur. Always consult your doctor before taking any supplements.

Articles on our website are presented for educational and informational purposes only. We do not recommend using article materials as medical advice. If you decide to take dietary supplements or make fundamental changes to your diet, first consult with a specialist.

Most of the therapeutic properties of alpha lipoic acid stem from its antioxidant status. Antioxidants are molecules that neutralize free radicals. Free radicals are waste products of the body that, when in excess, cause oxidative stress and damage cells.

Not only does alpha lipoic acid protect against oxidative stress, it also enhances the effectiveness of other antioxidants such as vitamin C and E. [R]

At the front of the throat is the thyroid gland, which is an important part of the endocrine system. One of its most important functions is the production of hormones that regulate maturation, growth and metabolism.

When thyroid health is compromised, hormones become out of balance. A 2021 study found that alpha lipoic acid, when taken with quercetin and resveratrol, normalizes thyroid hormone levels and reduces obesity caused by thyroid hormone imbalance. [R]

High blood glucose levels result from the body's inability to maintain normal insulin levels. Insulin helps glucose enter your cells. Without insulin, glucose accumulates and can lead to many serious health problems.

Diabetics develop severe nerve damage called diabetic neuropathy due to high blood sugar levels. ALA improves insulin sensitivity and reduces symptoms of this condition by improving microcirculation. According to several studies, alpha lipoic acid reduces the symptoms of damaged nerves (pain, numbness in the arms and legs, burning sensation).

The main benefit of alpha lipoic acid for diabetics is a reduced risk of neuropathic complications that affect the heart, as approximately 25 percent of people with diabetes develop cardiovascular autonomic neuropathy. It is characterized by reduced heart rate variability and is associated with an increased risk of mortality in people with diabetes.

Glutathione is considered a "master antioxidant" because it is critical for immunity, cellular health, and disease prevention. Research has shown that 300–1200 mg of alpha lipoic acid helps increase glutathione's ability to regulate the body's immune response. [R]

Topical creams containing 5% ALA help smooth out wrinkles caused by sun exposure. Skin damage is a side effect of high levels of free radicals, which is why fruits and vegetables containing antioxidants are thought to preserve youth. [R]

Blood vessels are lined by a single layer of cells called endothelium. When endothelial cells are healthy, they help relax blood vessels. The endothelial lining can be compromised by disease, leading to poor vascular health.

As we age, oxidative stress negatively impacts cardiovascular health. Chronic oxidative stress damages the endothelial tissue of the arteries and negatively affects blood flow. While poor heart function can lead to serious health problems, antioxidants help promote cardiovascular health. Alpha lipoic acid prevents cell death and improves heart function. [R]

Protects the brain

Alpha lipoic acid not only promotes neuronal regeneration, but also helps fight neurodegenerative disorders. Results from a study in stroke rats showed that ALA is beneficial for the treatment of ischemic stroke due to its neuroprotective and restorative properties. In another study, ALC reduced the mortality rate from 78% to 26%, within 24 hours of stroke onset. [R]

Improves vision

Oxidative stress can damage the nerves in the eyes and cause vision problems. Alpha lipoic acid has been used successfully to control symptoms of eye disorders, including vision loss, macular degeneration, retinal damage, cataracts, glaucoma, and Wilson's disease.

Research results show that long-term use of alpha lipoic acid has a beneficial effect on the development of retinopathy. As people age, their vision becomes increasingly impaired, so it is important to eat a nutrient-rich diet well into old age to prevent degeneration of eye tissue or early vision loss. [R]

Exercise is one of the best ways to achieve weight loss, healthy circulation and increased energy levels. Intense exercise can accelerate oxidative damage, which affects muscle tissue and cells.

Oxidative stress contributes to the pain you feel after strenuous exercise. Nutrients with antioxidant abilities, such as alpha lipoic acid, may help reduce this effect. Alpha lipoic acid supplements support intrinsic antioxidant defenses and reduce lipid peroxidation. [R]

As we age, oxidative stress negatively affects cells and causes aging. Research has examined the antioxidant properties of alpha lipoic acid. Some show that ALA reduces oxidative stress on skeletal muscle cells. Other studies have shown that ALA is useful in preventing the accumulation of excess iron in the cerebral cortex. [R]

Consumption of processed food, fast food and other unhealthy diet foods leads to obesity. A lifelong, proven plan for maintaining a healthy weight includes regular exercise and a balanced diet. However, nutrients like alpha lipoic acid can enhance the benefits of a healthy lifestyle. The study found that patients who took ALA experienced significant weight loss compared to the placebo group. [R]

Studies have shown that supplementing with alpha lipoic acid promotes liver health after exposure to various toxins and alcohol. [R]

Reduces the risk during pregnancy and improves the health of both mother and fetus.
Reduces the side effects of antipsychotic drugs.
Increases total sperm count, concentration and motility.
Prevents bone loss in women with osteopenia and bone loss in inflammatory conditions.
Increases life expectancy and fights lung and breast cancer.

In general, alpha lipoic acid supplementation in moderate amounts does not have significant side effects. The most common side effects were skin reactions (itching, rash or hives), as well as nausea and abdominal pain.

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When using lipoic acid, the body's reaction is not entirely expected. Side effects are rare, but if they occur, you should stop taking the supplement and consult a specialist. The following adverse reactions are observed:

aversion to food, complete loss of appetite;
constant headaches;
increased sweating and dry mouth;
sleep problems.

To prevent them from leading to serious health problems, it is necessary to take measures, and first of all, stop the drug.

Description and characteristics

Lipoic acid is an antioxidant. She, like all other representatives of this impressive group of chemical compounds, fights free radicals. Only if this fight is effective can we count on maintaining a balance of oxidation and reduction reactions in the body. This factor is one of the important components of the normal functioning of organs and systems.

Research on lipoic acid is still being conducted, but scientists already know a lot about it. The substance dissolves in fatty and aqueous media. Thanks to this, it can penetrate barriers that are an insurmountable barrier for other antioxidants. For example, a chemical compound reaches brain cells, stimulating the reactions necessary to cleanse the environment. The product is also capable of restoring vitamins C and E, coenzymes, i.e. other antioxidants.

Lipoic acid, reacting with enzymes, promotes energy production. It is also synthesized in the human body, but only in small quantities. Its volume can be replenished in different ways - with drugs or food. The most active substance is found in the following products:

Red meat, all types of liver.
Spinach, broccoli, white cabbage.
Milk.
Rice.
Brewer's yeast.
Carrots, beets, potatoes.

The chemical properties of lipoic acid contribute to their high-quality absorption. It is well received by the cells of the brain, liver, and nerves. The drug can be used not only as a prophylactic agent; it is often prescribed as part of complex treatment for a number of complex diseases.

Harm

There is no need to think that this antioxidant will not cause any harm to the body. If you take the drug incorrectly or use it excessively, the following side effects are possible:

Heartburn, stomach or intestinal upsets, nausea, skin rash, itchy skin; in severe cases, anaphylactic shock is possible.
A sharp drop in blood glucose levels. Therefore, persons suffering from diabetes should under no circumstances violate the drug dosage regimen and take it only under the supervision of a doctor.
Lipoate reduces the effectiveness of chemotherapy, so it is not recommended to combine them.
If you have problems with the thyroid gland and hormonal imbalance, you should use the substance with caution, as it can negatively affect hormonal levels.
Long-term use of the drug for peptic ulcers and gastritis can aggravate the problem. Also, for any other chronic diseases, long-term use is agreed with the doctor.

How to take it correctly?

Like other vitamin-like substances, lipoic acid has its own consumption standards. They will be different depending on age. Children under 15 years of age are recommended to take 12-25 mg per day, for adults - about 25-50 mg. During periods of intense physical or emotional stress, it is worth increasing your lipoic acid intake to 75 mg. If lipoic acid is part of a complex treatment program for any disease, then its dosage can be significantly increased.

Please note that while taking lipoic acid you must avoid drinking alcohol.

For what?

The properties of lipoic acid and its effects on the body are extensive.
This acid is best known for its antioxidant effects. Scientists from Moscow State University have proven that alpha-lipoic acid can increase the resistance of nerve cells to neurodegenerative disorders. The study was published in the journal Frontiers in Neuroscience.1 Its results may help in the development of drugs to treat diseases associated with disorders of the nervous tissue. Some studies have confirmed the effect of lipoic acid on increasing blood circulation.2

In terms of weight loss, studies conducted with obese people have seen weight loss in those who took 1800 mg of lipoic acid,3 but more research is needed to confidently claim that this supplement promotes weight loss. It slows down the accumulation of fat deposits, but you need to understand that if you want to lose weight, you cannot rely only on supplements. This drug can only be considered as an addition to exercise and diet.

It is also used to prevent and protect against infections and viruses. It takes part in many biochemical processes occurring in the body: it regulates fat and carbohydrate metabolism, promotes detoxification of the body after drinking alcohol, from toxic substances and heavy metals.

It is often prescribed as an additional means to reduce the side effects of basic drugs in the treatment of various diseases.

The supplement has a beneficial effect on the nervous system and reduces emotional stress.

This acid plays a critical role in the process of converting glucose into energy.

Alpha lipoic acid is a universal antioxidant because it dissolves not only in water, but also in fat. Thanks to this property, it copes well with intracellular protection. In addition, it combines well with other antioxidants, such as vitamin C, glutathione, vitamin E, enhancing their effects. Science has also proven the effectiveness of lipoic acid for memory problems.

Benefits for weight loss

To lose weight, lipoic acid should be consumed in the morning before the first meal, after training or at dinner. It is good to combine a portion of the supplement with carbohydrate foods.

To achieve maximum effect, you should strictly monitor your basic diet. It should be balanced and fully meet your daily needs for proteins, fats and carbohydrates. Avoid increasing feelings of hunger.

Helps maintain muscle mass while dieting

Another potential benefit of CLA is its ability to preserve muscle mass while dieting. The best way to maintain muscle mass during a long-term calorie-restricted diet is to consume adequate protein (1.6 g/kg+) with regular resistance training. However, supplementing with CLA can help improve your results.

The study, which lasted two years, looked at the body composition of overweight adults. Those who received 4.5 g of CLA showed a decrease in fat mass and preservation of muscle mass.4 However, it is worth noting that this two-year period did not include monitoring of diet and exercise. And when it comes to maintaining muscle while losing weight, these factors are important.

Supplement for athletes

Every athlete knows that during training, one of the main tasks in building a beautiful body is proper muscle recovery. Lipoic acid acts as an antioxidant and enhances human potential. When consumed, the production of heavy radicals decreases as a result of intense exercise in the gym. This allows the body to fully rest and grow. Regular use of lipoic acid will increase physical activity without losing performance. It also acts as an anti-catabolic, that is, it prevents proteins from being destroyed, which will have a beneficial effect on the effectiveness of your training process.

Application in cosmetology

Lipoic acid is actively used externally as a cosmetic product. In most compositions of anti-aging creams, it comes first. Lipoic acid gives the skin a healthy appearance, helps maintain its tone and reduces the negative effects of long exposure to the sun. It can be useful for skin diseases: dandruff and acne, as it narrows pores and reduces inflammation. A double-blind study of forty participants found a noticeable reduction in signs of skin aging after six months of supplementation.5