What is thyroxine
Thyroxine is a natural hormone that is present in the body of every healthy person. Without such a hormone, protein synthesis is impossible, and therefore the normal functioning of the digestive organs.
It is based on a synthetically created analogue of the hormone thyroxine. It is produced by the thyroid gland of the human body. The hormone is responsible for the process of protein breakdown. Under its influence, carbohydrates are converted into clean energy rather than stored as fat.
In the body of a person who suffers from excess weight, the hormone thyroxine is quite small. Therefore, it needs to be artificially replenished. This is why levothyroxine sodium was invented. Its common name is L-Thyroxine.
Anyone who has too little of the hormone or whose thyroid gland does not produce it for some reason often suffers from excess weight.
Hormone diagram
Thyroxine is capable of:
- increase the need of cells for oxygen;
- speed up metabolism in general;
- increase blood flow, sweating;
- remove excess water from the body;
- reduce appetite;
- increase endurance.
The synthetic analogue of the hormone, L-Thyroxine, has exactly the same abilities. Its benefits have been proven in practice experimentally.
L-thyroxine for weight loss dosage regimen. Taking the drug
Taking thyroxine for weight loss is possible only after consulting a doctor. Depending on the level of active substances of the thyroid gland, the body conditions are distinguished:
- Hypothyroidism. Body weight increases due to hormonal imbalance: deficiency of thyroid hormones against the background of high concentrations of TSH.
- Euthyroidism. The hormone ratio is normal. Weight gain occurs due to excess calories.
- Hyperthyroidism. High concentrations of thyroid hormones, body weight rapidly decreases.
The treatment regimen is different in each case. With hypothyroidism, reducing body weight is vital. The doctor diagnoses the disease, conducts tests to determine the concentration of the active substance, selects the drug and prescribes a treatment regimen.
Girls who only want to get rid of excess weight need to evaluate the balance of benefit and harm, since there is a high probability of harming their body. Be sure to consult with an endocrinologist regarding the dosage of the drug and its daily requirement.
Thyroxine 50 Berlin-Chemie for weight loss is the most common choice.
An L-thyroxine tablet contains 25, 50, 100 mcg of an artificial analogue of the hormone. Conventional treatment regimens:
- 25 mcg - half. Take 2 tablets per day;
- 50 mcg is the initial dose. It is divided into 2 doses of 25 mcg. The tablet is taken 1 hour before meals or 2 hours after meals (food disrupts the absorption of the hormone). Use the drug a second time before 18:00. To prevent heart rhythm problems, it is recommended to take a tablet (25 mg) of the beta blocker Metoprolol. This procedure must be repeated if in the afternoon the resting pulse is more than 70 beats per minute.
- 150-300 mcg is the daily dose of L-thyroxine. It is divided into three steps. The dosage of Metoprolol is also increased to 100 mg. A beta blocker is taken 2 times a day. If the pulse increases significantly, the Metoprolol dosage regimen is selected individually.
- Taking maximum doses of L-thyroxine requires constant monitoring of pulse, blood pressure, and general condition.
Additionally, you should consider:
- If missed, do not increase the medication intake the next day.
- The course is no more than 2 months.
- A month after starting treatment, you need to donate blood to determine the levels of TSH, T4, T3.
- The drug should be discontinued gradually, reducing the dosage over the course of a week.
- 4 weeks is a mandatory break between therapeutic courses.
- Beta blockers normalize heart function and reduce other adverse reactions.
Special recommendations:
While taking the drug, it is necessary to adjust the diet by reducing its calorie content. The menu is based on lean fish and meat, cereals, fresh vegetables and fruits.
The diet should include tomatoes, cucumbers, celery, lettuce, and lemons. They rid the body of harmful substances that disrupt the secretion of thyroid hormones. It is necessary to maintain sufficient drinking regime.
Be sure to increase physical activity. Practice strength exercises, morning exercises, walking.
Instructions for use for weight loss
To lose weight, you need to use the hormone correctly, in strictly defined doses.
The scheme is as follows: Start with 50 mcg. This dose is divided into 2 times, consumed throughout the day - morning and evening. After eating. If there is an irregular heart rhythm, take pills that block the hormone.
You should not consume more than 300 mcg of the drug per day. You cannot take more than 100 mcg at a time. These proportions are important, otherwise an increase in heart rate may occur, which will lead to fainting or stopping the “engine”.
If a person suffers from hypertension, the use of the drug is not recommended. For weight loss, the drug is recommended for 4-6 weeks. Then you must take a break for several months to avoid problems with blood pressure.
Dosage
The medication is available in different dosages of the hormone:
- 25 mcg;
- 50 mcg;
- 100 mcg.
It is impossible to find a drug with a dosage of 200 mcg. At least in Russian pharmacies. Here such a dosage is considered prohibited.
You are allowed to consume no more than 100 mcg at a time. The intake of the hormone into the body must be strictly controlled to avoid heart problems. If the dosage is exceeded, rhythm, pulse, and pressure surges may occur.
How to take l-thyroxine
As a general rule, you should take your thyroid medicine at the same time every day. However, if you forget to take your daily dose of thyroxine for weight loss, you should take it as soon as you remember, regardless of when or what you ate. If it is time to take your next scheduled dose, skip the forgotten dose. Do not take an additional dose unless specifically directed by your doctor.
It is better to start with 50 mg per day, dividing the dose into two parts of 25 mg. In the morning, it is advisable to drink 25 mg of the beta blocker metoprolol in order to prevent overload of the heart. Further, you can increase the dose gradually, up to 300 mcg per day, at intervals of three doses. Accordingly, the daily dose of Metoprolol can also be increased to 100 mg. Please note that you need to dose metoprolol according to how you feel, measuring your pulse. The course lasts from 4 to 7 weeks with a minimum break of 3 weeks. You need to stop as gradually as you started the course. In case of stomach upset in the form of diarrhea, take 1-2 capsules of loperamide.
Complex course of thyroxine with clenbuterol and yohimbine
If you want maximum effect, then naturally a complex of drugs will be more effective. Thyroxine does a good job of increasing the sensitivity of adrenergic receptors, through which yohimbine and clenbuterol act.
Contraindications
L-thyroxine, like any other drug, has contraindications. For the purpose of losing weight, it is prohibited to use it for those who suffer from:
- diabetes mellitus;
- history of heart attack;
- improper functioning of the kidneys and adrenal glands;
- the small intestine does not absorb;
- the person is galactose intolerant;
- have had thyrotoxicosis and its consequences in the past or present.
One of the relative contraindications is hypertension. If a person has any problems with the heart, pulse or blood pressure, taking the drug is not recommended. It would be a good idea to get at least a consultation with your attending physician so that in the future, after uncontrolled use of the drug, you do not end up in a hospital bed.
Optimal thyroid hormone levels
How to take it correctly: recommended doses and recipes
Instructions for use
The instructions for use actually mention weight loss as a result of taking the drug. But not as the main goal, but as one of the side effects. This is what may have caused it to be viewed as a diet pill. In fact, it is sometimes prescribed by doctors for this purpose also to patients whose obesity is caused precisely by a slowdown in metabolic processes. However, this is done after studying the results of a whole series of laboratory tests and in a strictly calculated dosage.
L-thyroxine is used illegally by professional bodybuilders to quickly get rid of fat and get a more defined body shape. In addition, it activates internal resources, increasing endurance and making training more effective. Here it is important to ensure that some time passes after taking the pill, otherwise, coupled with strength exercises, the load on the heart and blood vessels may be too great.
Only a doctor can correctly describe how to take L-thyroxine. It depends on the age, weight, health status and physical activity of the patient. However, there are some general rules that you need to know, even if you decide to take it yourself:
- The dosage is increased gradually and its use is also gradually stopped.
- If you have high blood pressure or heart problems, reduce the recommended dose by half.
- Take the tablets 30-40 minutes before meals, always with clean water.
- If you miss a dose, do not take a double dose as a replacement.
- Eliminate too fatty foods, confectionery and sweets from your diet.
L thyroxine instructions for use for weight loss :
- The initial dose of the drug is 50 mcg, it must be divided into 2 doses. In the afternoon, the tablet is taken strictly until 18:00. It is recommended to take the drug one hour before or two hours after a meal, as food reduces absorption. To avoid heart rhythm disturbances, you should take the beta blocker Metoprolol - 25 mg in the morning. If the heart rate (at rest) increases above 70 beats, it is recommended to take another 25 mg of Metoprolol in the afternoon.
- The maximum daily dose of L-thyroxine is from 150 to 300 mcg. This amount must be divided three times. The dose of Metoprolol should also be increased to 100 mg, taking a beta blocker twice a day. With an increased heart rate, the dosage of Metoprolol is selected individually.
- When the maximum dose of the hormone is reached, it is necessary to carefully monitor any changes in well-being and regularly measure blood pressure and pulse rate. When the pressure rises above 100/140 mm Hg. Art. the dose of Metoprolol should be adjusted upward.
Indications, contraindications and special recommendations
Since thyroxine for weight loss is a drug with a specific effect (it affects the activity of the thyroid gland), it is necessary to monitor blood pressure and heartbeat while taking the medicine. If the indicators increase and significantly exceed the norm, then it is recommended to take beta blockers (metaprolol, etc.). If diarrhea develops, loperamide may solve the problem.
Contraindications:
1. Increased levels of thyroid hormones in the blood - thyrotoxicosis. In this situation, hormone levels should be lowered, and not vice versa. Therefore, with this diagnosis, losing weight with L-thyroxine is strictly contraindicated,
2. Inflammation of the heart muscle and previous myocardial infarction,
3. Coronary heart disease, hypertension with a constant persistent increase in pressure,
4. Untreated adrenal insufficiency,
5. Diabetes mellitus,
6. Disorders of the digestive tract, which are expressed in impaired absorption function in the small intestine,
7. Individual sensitivity and intolerance to the components of the drug and allergic reactions
8. Galactose intolerance, which is most often a hereditary pathology. Lack of lactase, malabsorption of lactose and glucose,
9. Excessive amounts of thyroid hormones can lead to disturbances in nitrogen balance, it can become negative. As a consequence of this, carbohydrate metabolism is disrupted, the process of converting carbohydrates into fats is inhibited, and the water-salt balance of cellular structures is disrupted. There is a sudden, even with the expectation of such an effect, weight loss, increased excitability of the nervous system, tachycardia. There may be exophthalmos (bulging eyes),
10. Development of osteoporosis (low calcium content in bones, which leads to their increased fragility)
9. It is necessary to strictly adhere to the principle of stepwise increases in doses of the medication taken. Starting a course with too high a dose and sharply increasing it can lead to an increase in heart rate, drowsiness, attacks of nausea, and internal discomfort that is associated with unreasonable anxiety. You should also be wary of sudden weight loss. Such a development of the weight loss scenario will harm not only your health, but also your appearance - flabby and sagging skin is unlikely to add attractiveness and charm.
Trembling hands, excessive sweating, and diarrhea are also indicators of an overdose of the drug.
Indications for the use of L-thyroxine:
- Hypothyroidism,
- Prevention of goiter recurrence,
- Postoperative period for thyroid cancer,
- Diffuse toxic goiter,
- Diagnosis during a thyroid suspension test.
Side effects
Side effects from using L-thyroxine are pronounced. They may occur due to exceeding the recommended dose of the drug. In particular:
- heart failure;
- diarrhea, vomiting;
- aggression, hypersensitivity, excitability;
- lack of sleep;
- sharp pain in the head;
- failure or disappearance of menstruation in women;
- blood pressure surges;
- allergy;
- swelling;
- muscle tremors;
- lack of calcium in bones.
Use during pregnancy and breastfeeding
Can L-thyroxine be used during pregnancy and breastfeeding? There is not a word about this in contraindications. If an expectant or young mother intentionally uses the drug to lose weight, this should not be done.
The effect on the fetus and infant who is fed breast milk has not been proven and has not been thoroughly studied. But there is an opinion that L-thyroxine can cause rapid heartbeat in the fetus in the womb and in the newborn baby. Hence - increased heart rate, increased sweating - all this is not needed for a small person. Therefore, during the period of bearing a child and breastfeeding, it is better to refuse L-thyroxine.
L-Thyroxine analogues
There are quite a few analogues of L-thyroxine. They differ in the active ingredients in their composition and price. The following are suitable replacements for L-thyroxine:
- "THYROIDEA COMPOSITUUM";
- "ALBA";
- "YODINE-ACTIVE";
- "METABOLITES";
- "YODINE BALANCE";
- "HYPOTHYRONORM";
- "ALFIT-4";
- "SCHIZAREN";
- "ESPA-CARB";
- "ENDOCRINOL";
- "ENDONORM";
- "EUTIROX";
- "YODOMARIN".
What is the difference between T3 and T4B
The T4 drug is considered to be inactive. When a special enzyme is added to it, it becomes T3. It turns out to be a kind of prohormone. But its use can be dangerous. Causes sudden changes in hormonal levels. This negatively affects the condition of the thyroid gland. If you overdo it with T3, the thyroid gland will fail for a long time or fail completely. In this case, T4 is considered a safer option. In addition, T4 is cheaper than T3. This is, in general, what you need to know about their differences.
Reviews
Doctors
Nikita Aleksandrovich, endocrinologist, 9 years of work experience.
I regularly prescribe this drug, the dynamics of positive results is obvious - 8 out of 10. The drug also has a positive effect on weight loss in patients. All of the 10 patients lost weight.
Irina Olegovna, endocrinologist, 28 years of work experience.
An excellent hormonal drug. Copes perfectly with the functions assigned to it. Regarding weight loss, it occurs in those who additionally make changes to their usual diet. There are cases when patients lost up to 20 kg in a month and a half. This is a very fast weight loss.
Svetlana Nikolaevna, local therapist, 19 years of work experience.
I was faced with this situation: my patient, a 19-year-old girl, began to get sick with acute respiratory viral infections and acute respiratory infections more often. For a long time they could not understand what was leading to this, and later it turned out that her excess mass was disrupting the functioning of the whole organism. The girl went on a diet, but often broke down. She did not appear at the clinic for a long time. I recently saw her and didn’t recognize her. So at least minus 22 kg. She said that L-thyroxine helped. As a doctor, I understand that this is wrong, but as a woman I fully support her. The girl became healthier and happier, and she had a fiancé.
Reviews about the drug
Artem Zhuk, Voronezh: “In the gym, many people used L-thyroxine, I also decided to try it. The only thing I didn’t take into account was that my blood pressure was high. Because of my negligence and inattention to my health, I almost ended up in a hospital bed. I had to stop taking the drug..."
Mikhail, Engels: “I honestly didn’t believe in L-thyroxine. But I decided to try. I took it for about a month only in the strictly permitted dosage. I did not exceed these values. Everything is okay. I managed to lose about 5 kilograms without changing my diet or lifestyle in general. Satisfied… "
Elena, Moscow: “I dreamed of losing weight, I heard about the drug L-thyroxine and decided to try it. I immediately took a dose of 200 milligrams. A friend recommended this to me. Literally a few minutes later I felt a sharp dizziness and almost fainted. I decided not to experiment anymore.”
Anna Miroshnichenko, Khabarovsk: “I met L-thyroxine on the advice of a fitness trainer. I started taking 50 milligrams a day. My body had enough of this. I really lost weight. I think the drug works. But it must be taken correctly and very carefully. Too many side effects..."